Allogeneic stem cell transplantation for acute lymphocytic leukemia in adults - PubMed (original) (raw)

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Allogeneic stem cell transplantation for acute lymphocytic leukemia in adults

T G Martin et al. Hematol Oncol Clin North Am. 2001 Feb.

Abstract

Acute lymphocytic leukemia remains a difficult disease to treat in adults. Allogeneic bone marrow transplantation can cure some patients with ALL, but GVHD transplant-related mortality and disease relapse remain problematic. Immunotherapeutic approaches aimed at eliminating minimal residual disease and enhancing the GVL effect may decrease relapse rates and improve overall survival. Because of the rarity of this disease in adults, every new patient should be entered in well-designed, peer-reviewed, investigational trial.

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