Molecular pathogenesis of Citrobacter rodentium and transmissible murine colonic hyperplasia - PubMed (original) (raw)

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Molecular pathogenesis of Citrobacter rodentium and transmissible murine colonic hyperplasia

S A Luperchio et al. Microbes Infect. 2001 Apr.

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Abstract

Here we review the history, clinical significance, pathology and molecular pathogenesis of Citrobacter rodentium, the causative agent of transmissible murine colonic hyperplasia. C. rodentium serves as an important model pathogen for investigating the mechanisms controlling attaching and effacing pathology, epithelial hyperproliferation, and tumor promotion in the distal colon of the mouse.

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