The WWE domain: a common interaction module in protein ubiquitination and ADP ribosylation - PubMed (original) (raw)

The WWE domain: a common interaction module in protein ubiquitination and ADP ribosylation

L Aravind. Trends Biochem Sci. 2001 May.

Abstract

Sequence profile analysis was used to detect a conserved globular domain in several proteins including deltex, Trip12 and poly-ADP-ribose polymerase homologs. It was named the WWE domain after its most conserved residues and is predicted to mediate specific protein-protein interactions in ubiquitin and ADP-ribose conjugation systems.

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