Neuromuscular properties and fatigue in older men following acute creatine supplementation - PubMed (original) (raw)
Clinical Trial
Neuromuscular properties and fatigue in older men following acute creatine supplementation
J M Jakobi et al. Eur J Appl Physiol. 2001 Apr.
Abstract
The purpose of this study was to investigate the effects of creatine (Cr) supplementation in 12 older (65-82 years) men. The subjects were randomly assigned to a Cr or a placebo (P) group. Seven men were supplemented with 5 g of Cr and 5 g maltodextrin four times a day for 5 days (Cr), and 5 men consumed 5 g of maltodextrin four times a day for 5 days (P). Following this treatment body mass increased significantly in the Cr group (1 kg), but did not change in the P group, and measurements of arm anthropometry were not affected in either group. Prior to and following supplementation maximal isometric voluntary force (MVC), muscle activation, contractile properties and surface electromyography (EMG) were measured in the elbow flexor muscles at baseline, during a fatiguing task and over 10 min of recovery. The fatigue protocol involved both voluntary and contractile stimulated. Stimulated contractile properties, MVC, and muscle activation were not affected by Cr supplementation. Furthermore, there were no changes in time to fatigue, decline in MVC force, muscle activation, EMG or contractile properties during the fatigue protocol. The rates of recovery of voluntary force, and stimulated contractile force did not change following Cr supplementation. These results indicate that short-term Cr supplementation in older men does not influence isometric performance of the elbow flexor muscles.
Similar articles
- Contractile properties, fatigue and recovery are not influenced by short-term creatine supplementation in human muscle.
Jakobi JM, Rice CL, Curtin SV, Marsh GD. Jakobi JM, et al. Exp Physiol. 2000 Jul;85(4):451-60. Exp Physiol. 2000. PMID: 10918084 Clinical Trial. - Effect of short-term creatine supplementation on neuromuscular function.
Bazzucchi I, Felici F, Sacchetti M. Bazzucchi I, et al. Med Sci Sports Exerc. 2009 Oct;41(10):1934-41. doi: 10.1249/MSS.0b013e3181a2c05c. Med Sci Sports Exerc. 2009. PMID: 19727018 Clinical Trial. - The effect of creatine loading on neuromuscular fatigue in women.
Smith-Ryan AE, Ryan ED, Fukuda DH, Costa PB, Cramer JT, Stout JR. Smith-Ryan AE, et al. Med Sci Sports Exerc. 2014;46(5):990-7. doi: 10.1249/MSS.0000000000000194. Med Sci Sports Exerc. 2014. PMID: 24152706 Clinical Trial. - Creatine supplementation does not alter neuromuscular recovery after eccentric exercise.
Boychuk KE, Lanovaz JL, Krentz JR, Lishchynsky JT, Candow DG, Farthing JP. Boychuk KE, et al. Muscle Nerve. 2016 Sep;54(3):487-95. doi: 10.1002/mus.25091. Epub 2016 Jul 4. Muscle Nerve. 2016. PMID: 26930603 Clinical Trial. - Effects of 30 days of creatine ingestion in older men.
Rawson ES, Wehnert ML, Clarkson PM. Rawson ES, et al. Eur J Appl Physiol Occup Physiol. 1999 Jul;80(2):139-44. doi: 10.1007/s004210050570. Eur J Appl Physiol Occup Physiol. 1999. PMID: 10408325 Clinical Trial.
Cited by
- Fueling the Firefighter and Tactical Athlete with Creatine: A Narrative Review of a Key Nutrient for Public Safety.
Gonzalez DE, Forbes SC, Zapp A, Jagim A, Luedke J, Dickerson BL, Root A, Gil A, Johnson SE, Coles M, Brager A, Sowinski RJ, Candow DG, Kreider RB. Gonzalez DE, et al. Nutrients. 2024 Sep 28;16(19):3285. doi: 10.3390/nu16193285. Nutrients. 2024. PMID: 39408252 Free PMC article. Review. - The Combination of Lactoferrin and Creatine Ameliorates Muscle Decay in a Sarcopenia Murine Model.
Wu W, Guo X, Qu T, Huang Y, Tao J, He J, Wang X, Luo J, An P, Zhu Y, Sun Y, Luo Y. Wu W, et al. Nutrients. 2024 Jun 19;16(12):1958. doi: 10.3390/nu16121958. Nutrients. 2024. PMID: 38931310 Free PMC article. - Creatine Supplementation to Improve Sarcopenia in Chronic Liver Disease: Facts and Perspectives.
Casciola R, Leoni L, Cuffari B, Pecchini M, Menozzi R, Colecchia A, Ravaioli F. Casciola R, et al. Nutrients. 2023 Feb 8;15(4):863. doi: 10.3390/nu15040863. Nutrients. 2023. PMID: 36839220 Free PMC article. Review. - Effects of Protein, Essential Amino Acids, B-Hydroxy B-Methylbutyrate, Creatine, Dehydroepiandrosterone and Fatty Acid Supplementation on Muscle Mass, Muscle Strength and Physical Performance in Older People Aged 60 Years and Over. A Systematic Review on the Literature.
Beaudart C, Rabenda V, Simmons M, Geerinck A, Araujo De Carvalho I, Reginster JY, Amuthavalli Thiyagarajan J, Bruyère O. Beaudart C, et al. J Nutr Health Aging. 2018;22(1):117-130. doi: 10.1007/s12603-017-0934-z. J Nutr Health Aging. 2018. PMID: 29300431 - Effect of creatine supplementation during resistance training on lean tissue mass and muscular strength in older adults: a meta-analysis.
Chilibeck PD, Kaviani M, Candow DG, Zello GA. Chilibeck PD, et al. Open Access J Sports Med. 2017 Nov 2;8:213-226. doi: 10.2147/OAJSM.S123529. eCollection 2017. Open Access J Sports Med. 2017. PMID: 29138605 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical