Dietary fat intake and risk of type 2 diabetes in women - PubMed (original) (raw)
. 2001 Jun;73(6):1019-26.
doi: 10.1093/ajcn/73.6.1019.
Affiliations
- PMID: 11382654
- DOI: 10.1093/ajcn/73.6.1019
Dietary fat intake and risk of type 2 diabetes in women
J Salmerón et al. Am J Clin Nutr. 2001 Jun.
Abstract
Background: The long-term relations between specific types of dietary fat and risk of type 2 diabetes remain unclear.
Objective: Our objective was to examine the relations between dietary fat intakes and the risk of type 2 diabetes.
Design: We prospectively followed 84204 women aged 34-59 y with no diabetes, cardiovascular disease, or cancer in 1980. Detailed dietary information was assessed at baseline and updated in 1984, 1986, and 1990 by using validated questionnaires. Relative risks of type 2 diabetes were obtained from pooled logistic models adjusted for nondietary and dietary covariates.
Results: During 14 y of follow-up, 2507 incident cases of type 2 diabetes were documented. Total fat intake, compared with equivalent energy intake from carbohydrates, was not associated with risk of type 2 diabetes; for a 5% increase in total energy from fat, the relative risk (RR) was 0.98 (95% CI: 0.94, 1.02). Intakes of saturated or monounsaturated fatty acids were also not significantly associated with the risk of diabetes. However, for a 5% increase in energy from polyunsaturated fat, the RR was 0.63 (0.53, 0.76; P < 0.0001) and for a 2% increase in energy from trans fatty acids the RR was 1.39 (1.15, 1.67; P = 0.0006). We estimated that replacing 2% of energy from trans fatty acids isoenergetically with polyunsaturated fat would lead to a 40% lower risk (RR: 0.60; 95% CI: 0.48, 0.75).
Conclusions: These data suggest that total fat and saturated and monounsaturated fatty acid intakes are not associated with risk of type 2 diabetes in women, but that trans fatty acids increase and polyunsaturated fatty acids reduce risk. Substituting nonhydrogenated polyunsaturated fatty acids for trans fatty acids would likely reduce the risk of type 2 diabetes substantially.
Comment in
- Do trans fatty acids increase the incidence of type 2 diabetes?
Clandinin MT, Wilke MS. Clandinin MT, et al. Am J Clin Nutr. 2001 Jun;73(6):1001-2. doi: 10.1093/ajcn/73.6.1001. Am J Clin Nutr. 2001. PMID: 11382650 No abstract available. - Long-chain polyunsaturated fatty acids and diabetes mellitus.
Das UN. Das UN. Am J Clin Nutr. 2002 Apr;75(4):780-1. doi: 10.1093/ajcn/75.4.780. Am J Clin Nutr. 2002. PMID: 11916768 No abstract available.
Similar articles
- Dietary fat and cholesterol and the risk of cardiovascular disease among women with type 2 diabetes.
Tanasescu M, Cho E, Manson JE, Hu FB. Tanasescu M, et al. Am J Clin Nutr. 2004 Jun;79(6):999-1005. doi: 10.1093/ajcn/79.6.999. Am J Clin Nutr. 2004. PMID: 15159229 - Dietary Fats in Relation to Total and Cause-Specific Mortality in a Prospective Cohort of 521 120 Individuals With 16 Years of Follow-Up.
Zhuang P, Zhang Y, He W, Chen X, Chen J, He L, Mao L, Wu F, Jiao J. Zhuang P, et al. Circ Res. 2019 Mar;124(5):757-768. doi: 10.1161/CIRCRESAHA.118.314038. Circ Res. 2019. PMID: 30636521 - [Dietary fat and ischemic stroke risk in Northern Portugal].
Monteiro I, Vaz Almeid MD. Monteiro I, et al. Acta Med Port. 2007 Jul-Aug;20(4):307-18. Epub 2007 Nov 15. Acta Med Port. 2007. PMID: 18198074 Portuguese. - The role of dietary fats for preventing cardiovascular disease. A review.
Szostak-Wegierek D, Kłosiewicz-Latoszek L, Szostak WB, Cybulska B. Szostak-Wegierek D, et al. Rocz Panstw Zakl Hig. 2013;64(4):263-9. Rocz Panstw Zakl Hig. 2013. PMID: 24693710 Review. - Diet and risk of Type II diabetes: the role of types of fat and carbohydrate.
Hu FB, van Dam RM, Liu S. Hu FB, et al. Diabetologia. 2001 Jul;44(7):805-17. doi: 10.1007/s001250100547. Diabetologia. 2001. PMID: 11508264 Review.
Cited by
- An evidence-based assessment of the nutritional recommendations for the prevention of diabetes mellitus.
Kechagia I, Panagiotakos D. Kechagia I, et al. Hormones (Athens). 2024 Sep 17. doi: 10.1007/s42000-024-00604-4. Online ahead of print. Hormones (Athens). 2024. PMID: 39287760 Review. - Nutrient quality in dietary therapy for diabetes and diabetic kidney disease.
Tsuruta H, Sugahara S, Kume S. Tsuruta H, et al. J Diabetes Investig. 2024 Aug;15(8):973-981. doi: 10.1111/jdi.14208. Epub 2024 Apr 9. J Diabetes Investig. 2024. PMID: 38591876 Free PMC article. Review. - Nutrition at the Intersection between Gut Microbiota Eubiosis and Effective Management of Type 2 Diabetes.
Hamamah S, Iatcu OC, Covasa M. Hamamah S, et al. Nutrients. 2024 Jan 16;16(2):269. doi: 10.3390/nu16020269. Nutrients. 2024. PMID: 38257161 Free PMC article. Review. - A novel type of Brassica napus with higher stearic acid in seeds developed through genome editing of BnaSAD2 family.
Huang H, Ahmar S, Samad RA, Qin P, Yan T, Zhao Q, Xie K, Zhang C, Fan C, Zhou Y. Huang H, et al. Theor Appl Genet. 2023 Aug 12;136(9):187. doi: 10.1007/s00122-023-04414-x. Theor Appl Genet. 2023. PMID: 37572171 - Association between fatty acids and the risk of impaired glucose tolerance and type 2 diabetes mellitus in American adults: NHANES 2005-2016.
Zhu X, Chen L, Lin J, Ba M, Liao J, Zhang P, Zhao C. Zhu X, et al. Nutr Diabetes. 2023 May 1;13(1):8. doi: 10.1038/s41387-023-00236-4. Nutr Diabetes. 2023. PMID: 37127641 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical