Coordinate regulation of metabotropic glutamate receptors - PubMed (original) (raw)

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Coordinate regulation of metabotropic glutamate receptors

S Alagarsamy et al. Curr Opin Neurobiol. 2001 Jun.

Abstract

Recent studies aimed at identifying the mechanisms that regulate the signaling of metabotropic glutamate receptors (mGluRs) have revealed that both protein kinase and protein phosphatase activity are important in directly modulating mGluR function. The inter-relationship between phosphorylation and dephosphorylation of mGluRs seems to be an important determinant in regulating mGluR function and the subsequent neuromodulatory events elicited by activation of mGluRs.

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