Antimicrobial resistance prevalence rates in hospital antibiograms reflect prevalence rates among pathogens associated with hospital-acquired infections - PubMed (original) (raw)

. 2001 Aug 1;33(3):324-30.

doi: 10.1086/321893. Epub 2001 Jun 21.

Affiliations

• PMID: 11438897
• DOI: 10.1086/321893

Antimicrobial resistance prevalence rates in hospital antibiograms reflect prevalence rates among pathogens associated with hospital-acquired infections

S K Fridkin et al. Clin Infect Dis. 2001.

Abstract

To determine whether routine antibiograms (summaries reporting resistance of all tested isolates) reflect resistance rates among pathogens associated with hospital-acquired infections, we compared data collected from 2 different surveillance components in the same 166 intensive care units (ICUs). ICUs reported data during the same months to both the infection-based surveillance and the laboratory-based surveillance. Paired comparisons of the percentage of isolates resistant were made between systems within each ICU. No significant differences existed (P>.05) between the percentage of isolates resistant from the infection-based system and laboratory-based system for all antimicrobial-resistant organisms studied, except methicillin resistance in Staphylococcus species. The mean difference in percentage resistance was higher from the infection-based system than the laboratory-based system for S. aureus (mean difference, +8%, P<.001) and coagulase-negative staphylococci (mean difference, +9%, P<.001). Overall, hospital antibiograms reflected susceptibility patterns among isolates associated with hospital-acquired infections. Hospital antibiograms may underestimate the relative frequency of methicillin resistance among Staphylococcus species when associated with hospital-acquired infections.

PubMed Disclaimer

Similar articles

• Susceptibility of Staphylococcus aureus isolated from skin and wound infections in the United States 2005-07: laboratory-based surveillance study.
  Tillotson GS, Draghi DC, Sahm DF, Tomfohrde KM, Del Fabro T, Critchley IA. Tillotson GS, et al. J Antimicrob Chemother. 2008 Jul;62(1):109-15. doi: 10.1093/jac/dkn149. Epub 2008 Apr 8. J Antimicrob Chemother. 2008. PMID: 18397923
• Occurrence and antimicrobial resistance pattern comparisons among bloodstream infection isolates from the SENTRY Antimicrobial Surveillance Program (1997-2002).
  Biedenbach DJ, Moet GJ, Jones RN. Biedenbach DJ, et al. Diagn Microbiol Infect Dis. 2004 Sep;50(1):59-69. doi: 10.1016/j.diagmicrobio.2004.05.003. Diagn Microbiol Infect Dis. 2004. PMID: 15380279
• [Microbiological isolates associated with nosocomial infections in intensive care units: data of 274 intensive care units participating in the German Nosocomial Infections Surveillance System (KISS)].
  Geffers C, Zuschneid I, Sohr D, Rüden H, Gastmeier P. Geffers C, et al. Anasthesiol Intensivmed Notfallmed Schmerzther. 2004 Jan;39(1):15-9. doi: 10.1055/s-2004-815713. Anasthesiol Intensivmed Notfallmed Schmerzther. 2004. PMID: 14740311 German.
• Evolving problems with resistant pathogens.
  Chastre J. Chastre J. Clin Microbiol Infect. 2008 Apr;14 Suppl 3:3-14. doi: 10.1111/j.1469-0691.2008.01958.x. Clin Microbiol Infect. 2008. PMID: 18318874 Review.

Cited by

• Comparison of hospital-wide and unit-specific cumulative antibiograms in hospital- and community-acquired infection.
  Lamoth F, Wenger A, Prod'hom G, Vallet Y, Plüss-Suard C, Bille J, Zanetti G. Lamoth F, et al. Infection. 2010 Aug;38(4):249-53. doi: 10.1007/s15010-010-0033-0. Epub 2010 Jun 16. Infection. 2010. PMID: 20552386
• Impact of an antimicrobial utilization program on antimicrobial use at a large teaching hospital: a randomized controlled trial.
  Camins BC, King MD, Wells JB, Googe HL, Patel M, Kourbatova EV, Blumberg HM. Camins BC, et al. Infect Control Hosp Epidemiol. 2009 Oct;30(10):931-8. doi: 10.1086/605924. Infect Control Hosp Epidemiol. 2009. PMID: 19712032 Free PMC article. Clinical Trial.
• Antimicrobial susceptibility testing using high surface-to-volume ratio microchannels.
  Chen CH, Lu Y, Sin ML, Mach KE, Zhang DD, Gau V, Liao JC, Wong PK. Chen CH, et al. Anal Chem. 2010 Feb 1;82(3):1012-9. doi: 10.1021/ac9022764. Anal Chem. 2010. PMID: 20055494 Free PMC article.
• Prevalence and antibiogram profiling of Escherichia coli pathotypes isolated from the Kat River and the Fort Beaufort abstraction water.
  Nontongana N, Sibanda T, Ngwenya E, Okoh AI. Nontongana N, et al. Int J Environ Res Public Health. 2014 Aug 12;11(8):8213-27. doi: 10.3390/ijerph110808213. Int J Environ Res Public Health. 2014. PMID: 25119699 Free PMC article.
• Analysis and Presentation of Cumulative Antimicrobial Susceptibility Test Data--The Influence of Different Parameters in a Routine Clinical Microbiology Laboratory.
  Kohlmann R, Gatermann SG. Kohlmann R, et al. PLoS One. 2016 Jan 27;11(1):e0147965. doi: 10.1371/journal.pone.0147965. eCollection 2016. PLoS One. 2016. PMID: 26814675 Free PMC article.

Publication types

MeSH terms

LinkOut - more resources

• Full Text Sources

  • Ovid Technologies, Inc.
  • Silverchair Information Systems

• Other Literature Sources

  • The Lens - Patent Citations Database

• Medical

  • MedlinePlus Health Information