Somatic activation of beta-catenin bypasses pre-TCR signaling and TCR selection in thymocyte development - PubMed (original) (raw)

Glycogen synthase kinase 3 drives thymocyte egress by suppressing β-catenin activation of Akt.

Liu C, Ma L, Wang Y, Zhao J, Chen P, Chen X, Wang Y, Hu Y, Liu Y, Jia X, Yang Z, Yin X, Wu J, Wu S, Zheng H, Ma X, Sun X, He Y, Lin L, Fu Y, Liao K, Zhou X, Jiang S, Fu G, Tang J, Han W, Chen XL, Fan W, Hong Y, Han J, Huang X, Li BA, Xiao N, Xiao C, Fu G, Liu WH. Liu C, et al. Sci Adv. 2021 Oct 8;7(41):eabg6262. doi: 10.1126/sciadv.abg6262. Epub 2021 Oct 8. Sci Adv. 2021. PMID: 34623920 Free PMC article.