The effect of low-dose combined oral contraceptive pills versus injectable contraceptive (Depot Provera) on liver function tests of women with compensated bilharzial liver fibrosis - PubMed (original) (raw)
Clinical Trial
The effect of low-dose combined oral contraceptive pills versus injectable contraceptive (Depot Provera) on liver function tests of women with compensated bilharzial liver fibrosis
A H Tagy et al. Contraception. 2001 Sep.
Abstract
This was an open comparative trial of two types of hormonal contraceptives, a low-dose combined oral contraceptive and the injectable depot-medroxyprogerone acetate, with a control group using an intrauterine device (copper T-380). Clients were recruited from bilharzial patients attending the maternal-child health and family centers affiliated with the National Liver Institute. Clients with compensated bilharzial liver disease were chosen and were divided into three subgroups according to their own preference for the method of contraception. Baseline, 2-, and 4-months liver function tests were compared, and abdominal ultrasound scanning of the liver was done. There was a nonsignificant change in liver function tests, and the portal vein diameter measured by ultrasound scanning was not changed with steroidal contraceptives. The use of combined oral contraceptive containing low-dose estrogen or using depot medroxyprogertone acetate injectables are safe and can be prescribed in cases with compensated bilharzial hepatic fibrosis with normal function.
Similar articles
- Liver function tests and low-dose estrogen oral contraceptives.
Dickerson J, Bressler R, Christian CD. Dickerson J, et al. Contraception. 1980 Dec;22(6):597-603. doi: 10.1016/0010-7824(80)90086-4. Contraception. 1980. PMID: 7214908 - Depot medroxyprogesterone acetate versus an oral contraceptive combined with very-low-dose danazol for long-term treatment of pelvic pain associated with endometriosis.
Vercellini P, De Giorgi O, Oldani S, Cortesi I, Panazza S, Crosignani PG. Vercellini P, et al. Am J Obstet Gynecol. 1996 Aug;175(2):396-401. doi: 10.1016/s0002-9378(96)70152-7. Am J Obstet Gynecol. 1996. PMID: 8765259 Clinical Trial. - Effect of oral contraceptive on liver function tests of women with schistosomiasis in the Philippines.
Sy FS, Osteria TS, Opiniano V, Gler S. Sy FS, et al. Contraception. 1986 Sep;34(3):283-94. doi: 10.1016/0010-7824(86)90009-0. Contraception. 1986. PMID: 3098499 - Once-a-month injectable contraceptives: efficacy and reasons for discontinuation.
Koetsawang S. Koetsawang S. Contraception. 1994 Apr;49(4):387-98. doi: 10.1016/0010-7824(94)90034-5. Contraception. 1994. PMID: 8013221 Review. - Pharmacodynamic effects of once-a-month combined injectable contraceptives.
Sang GW. Sang GW. Contraception. 1994 Apr;49(4):361-85. doi: 10.1016/0010-7824(94)90033-7. Contraception. 1994. PMID: 8013220 Review.
Cited by
- U.S. Medical Eligibility Criteria for Contraceptive Use, 2024.
Nguyen AT, Curtis KM, Tepper NK, Kortsmit K, Brittain AW, Snyder EM, Cohen MA, Zapata LB, Whiteman MK; Contributors. Nguyen AT, et al. MMWR Recomm Rep. 2024 Aug 8;73(4):1-126. doi: 10.15585/mmwr.rr7304a1. MMWR Recomm Rep. 2024. PMID: 39106314 Free PMC article.