Venous occlusion plethysmography in cardiovascular research: methodology and clinical applications - PubMed (original) (raw)

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Venous occlusion plethysmography in cardiovascular research: methodology and clinical applications

I B Wilkinson et al. Br J Clin Pharmacol. 2001 Dec.

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Figures

Figure 1

Figure 1

Assessment of forearm blood flow using venous occlusion plethysmography.

Figure 2

Figure 2

Effect of intra-arterial substance P on forearm blood flow. 2 pmol min−1 substance P produces a marked increase in blood flow in the infused arm, as illustrated by the increase in the slope of the tracing.

Figure 3

Figure 3

Determination of venous distensibility. Changes in forearm volume (FAV), arterial pressure (AP), and transmural pressure (TMVP) – occluding cuff pressure, when TMPV was increased in a step-wise manner. From [33] with permission.

Figure 4

Figure 4

Determination of capillary permeability. A simulated response to inflation of the upper arm cuff. There is a rapid increase in forearm volume _V_a, followed by a slower continued rise in volume of slope _J_v, due to movement of fluid from the capillaries into the forearm. From [30] with permission.

Figure 5

Figure 5

Effect of atrial natriuretic peptide on capillary permeability. Effect of a control infusion, sodium nitroprusside (SNP) and atrial natriuretic peptide (ANP) on forearm volume (FAV) during prolonged cuff inflation to 30 mmHg. From [33] with permission.

Figure 6

Figure 6

Effect of angiotensin II and bradykinin on forearm blood flow. FBF in the infused (▪) and noninfused (□) arm, during infusion of the two peptides. From [40] with permission.

Figure 7

Figure 7

Effect of acetylcholine and sodium nitroprusside on forearm blood flow in hypertensive and normotensive individuals. FBF in the infused arm of hypertensive (•) and normotensive (○) individuals in response to an intra-arterial incremental infusion of acetylcholine and sodium nitroprusside. As shown, the response to acetylcholine but not nitroprusside is blunted in the hypertensive subjects. From [109] with permission.

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