Cyclic ADP ribose as a calcium-mobilizing messenger - PubMed (original) (raw)
Review
. 2000 Jul 18;2000(41):pe1.
doi: 10.1126/stke.2000.41.pe1.
Affiliations
- PMID: 11752598
- DOI: 10.1126/stke.2000.41.pe1
Review
Cyclic ADP ribose as a calcium-mobilizing messenger
A Galione et al. Sci STKE. 2000.
Abstract
This Perspective by Galione and Churchill is one in a series on intracellular calcium release mechanisms. The authors review the evidence for cyclic adenosine diphosphate ribose (cADPR) being a second messenger involved in regulating intracellular calcium. In addition, the physiological stimuli and responses mediated by cADPR are discussed. The Perspective is accompanied by a movie showing a calcium wave triggered by cADPR.
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