Phagocytosis and innate immunity - PubMed (original) (raw)
Review
Phagocytosis and innate immunity
Steven Greenberg et al. Curr Opin Immunol. 2002 Feb.
Abstract
Phagocytosis is an evolutionarily conserved process utilized by many cells to ingest microbial pathogens, and apoptotic and necrotic corpses. Recent investigation has revealed a fundamental requirement for two co-ordinated cellular processes--cytoskeletal alterations and membrane trafficking--in the phagocytic event. Some elements of this machinery are co-opted by certain pathogens to gain entry into host cells.
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