Epigenetics as a first exit problem - PubMed (original) (raw)

Epigenetics as a first exit problem

E Aurell et al. Phys Rev Lett. 2002.

Abstract

We develop a framework to discuss the stability of epigenetic states as first exit problems in dynamical systems with noise. We consider in particular the stability of the lysogenic state of the lambda prophage. The formalism defines a quantitative measure of robustness of inherited states.

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