MAP kinase cascades: scaffolding signal specificity - PubMed (original) (raw)
Review
. 2002 Jan 22;12(2):R53-5.
doi: 10.1016/s0960-9822(01)00672-8.
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- PMID: 11818078
- DOI: 10.1016/s0960-9822(01)00672-8
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Review
MAP kinase cascades: scaffolding signal specificity
Frank van Drogen et al. Curr Biol. 2002.
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Abstract
Scaffold proteins organize many MAP kinase pathways by interacting with several components of these cascades. Recent studies suggest that scaffold proteins provide local activation platforms that contribute to signal specificity by insulating different MAP kinase pathways.
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