ECM remodeling regulates angiogenesis: endothelial integrins look for new ligands - PubMed (original) (raw)
Review
. 2002 Feb 12;2002(119):pe7.
doi: 10.1126/stke.2002.119.pe7.
Affiliations
- PMID: 11842241
- DOI: 10.1126/stke.2002.119.pe7
Review
ECM remodeling regulates angiogenesis: endothelial integrins look for new ligands
Dwayne G Stupack et al. Sci STKE. 2002.
Abstract
The process of angiogenesis is a dynamic one. Vascular endothelial cells are changing at the same time the extracellular matrix is being remodeled. Stupack and Cheresh discuss how remodeling of the extracellular matrix (ECM) and changes in the endothelial cell protein production and integrin expression contribute to the complex process of new blood vessel growth from an existing vascular bed.
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