The sigma(70)-like motif: a eukaryotic RNA binding domain unique to a superfamily of proteins required for ribosome biogenesis - PubMed (original) (raw)
Comparative Study
The sigma(70)-like motif: a eukaryotic RNA binding domain unique to a superfamily of proteins required for ribosome biogenesis
Karen A Wehner et al. Mol Cell. 2002 Feb.
Free article
Abstract
Little is understood about the role of nucleolar RNA binding proteins in ribosome biogenesis, although there is a clear need for them based on the strict folding requirements of the pre-rRNA. We have identified a superfamily of RNA binding proteins whose members are required for different stages of ribosome biogenesis. The Imp4 superfamily is composed of five individual families (Imp4, Rpf1, Rpf2, Brx1, and Ssf) that all possess the sigma(70)-like motif, a eukaryotic RNA binding domain with prokaryotic origins. The Imp4 superfamily members associate with RNAs that are consistent with their distinct roles in ribosome biogenesis and suggest the mechanisms by which they function.
Similar articles
- The role of small nucleolar ribonucleoproteins in ribosome synthesis.
Tollervey D, Hurt EC. Tollervey D, et al. Mol Biol Rep. 1990;14(2-3):103-6. doi: 10.1007/BF00360433. Mol Biol Rep. 1990. PMID: 2141891 Review. No abstract available. - Subcellular localization of ribosomal P0-like protein MRT4 is determined by its N-terminal domain.
Michalec B, Krokowski D, Grela P, Wawiórka L, Sawa-Makarska J, Grankowski N, Tchórzewski M. Michalec B, et al. Int J Biochem Cell Biol. 2010 May;42(5):736-48. doi: 10.1016/j.biocel.2010.01.011. Epub 2010 Jan 18. Int J Biochem Cell Biol. 2010. PMID: 20083226 - The N-terminal extension of yeast ribosomal protein L8 is involved in two major remodeling events during late nuclear stages of 60S ribosomal subunit assembly.
Tutuncuoglu B, Jakovljevic J, Wu S, Gao N, Woolford JL Jr. Tutuncuoglu B, et al. RNA. 2016 Sep;22(9):1386-99. doi: 10.1261/rna.055798.115. Epub 2016 Jul 7. RNA. 2016. PMID: 27390266 Free PMC article. - Deletion of the three distal S1 motifs of Saccharomyces cerevisiae Rrp5p abolishes pre-rRNA processing at site A(2) without reducing the production of functional 40S subunits.
Vos HR, Faber AW, de Gier MD, Vos JC, Raué HA. Vos HR, et al. Eukaryot Cell. 2004 Dec;3(6):1504-12. doi: 10.1128/EC.3.6.1504-1512.2004. Eukaryot Cell. 2004. PMID: 15590824 Free PMC article. - Ribosomal RNA processing and ribosome biogenesis in eukaryotes.
Nazar RN. Nazar RN. IUBMB Life. 2004 Aug;56(8):457-65. doi: 10.1080/15216540400010867. IUBMB Life. 2004. PMID: 15545225 Review.
Cited by
- The molecular basis for ANE syndrome revealed by the large ribosomal subunit processome interactome.
McCann KL, Teramoto T, Zhang J, Tanaka Hall TM, Baserga SJ. McCann KL, et al. Elife. 2016 Apr 14;5:e16381. doi: 10.7554/eLife.16381. Elife. 2016. PMID: 27077951 Free PMC article. - Crystal structure of Mil (Mth680): internal duplication and similarity between the Imp4/Brix domain and the anticodon-binding domain of class IIa aminoacyl-tRNA synthetases.
Ng CL, Waterman D, Koonin EV, Antson AA, Ortiz-Lombardía M. Ng CL, et al. EMBO Rep. 2005 Feb;6(2):140-6. doi: 10.1038/sj.embor.7400328. EMBO Rep. 2005. PMID: 15654320 Free PMC article. - Human RPF1 and ESF1 in Pre-rRNA Processing and the Assembly of Pre-Ribosomal Particles: A Functional Study.
Deryabin A, Moraleva A, Dobrochaeva K, Kovaleva D, Rubtsova M, Dontsova O, Rubtsov Y. Deryabin A, et al. Cells. 2024 Feb 10;13(4):326. doi: 10.3390/cells13040326. Cells. 2024. PMID: 38391939 Free PMC article. - Nop9 is a PUF-like protein that prevents premature cleavage to correctly process pre-18S rRNA.
Zhang J, McCann KL, Qiu C, Gonzalez LE, Baserga SJ, Hall TM. Zhang J, et al. Nat Commun. 2016 Oct 11;7:13085. doi: 10.1038/ncomms13085. Nat Commun. 2016. PMID: 27725644 Free PMC article. - RNA polymerase I transcription and pre-rRNA processing are linked by specific SSU processome components.
Gallagher JE, Dunbar DA, Granneman S, Mitchell BM, Osheim Y, Beyer AL, Baserga SJ. Gallagher JE, et al. Genes Dev. 2004 Oct 15;18(20):2506-17. doi: 10.1101/gad.1226604. Genes Dev. 2004. PMID: 15489292 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Molecular Biology Databases