Guanidinium-CsCl density gradients for isopycnic analysis of nucleic acids - PubMed (original) (raw)
Guanidinium-CsCl density gradients for isopycnic analysis of nucleic acids
V Enea et al. Science. 1975.
Abstract
The addition of guanidinium chloride to CsCl gradients lowers the apparent density of RNA, DNA, and hybrid polymers in such a way that all three can be banded, fractionated, and analyzed in one gradient with essentially no damage to their chemical integrity or to their biological activity.
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