The contribution of nuclear compartmentalization to gene regulation - PubMed (original) (raw)
Review
. 2002 Feb 22;108(4):513-21.
doi: 10.1016/s0092-8674(02)00650-5.
Affiliations
- PMID: 11909522
- DOI: 10.1016/s0092-8674(02)00650-5
Free article
Review
The contribution of nuclear compartmentalization to gene regulation
Maria Carmo-Fonseca. Cell. 2002.
Free article
Abstract
Recent developments in live-cell imaging are challenging our stereotyped view of the fixed cell nucleus. The emerging picture is that nuclear processes may rely on a constant flow of molecules between dynamic compartments created by relatively immobile binding or assembly sites. This article discusses current views on the origins of nuclear compartments and their roles in gene expression.