Gene-specific regulation by general translation factors - PubMed (original) (raw)

Review

. 2002 Feb 22;108(4):545-56.

doi: 10.1016/s0092-8674(02)00642-6.

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• PMID: 11909525
• DOI: 10.1016/s0092-8674(02)00642-6

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Review

Gene-specific regulation by general translation factors

Thomas E Dever. Cell. 2002.

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Abstract

Protein synthesis is the ultimate step of gene expression and a key control point for regulation. In particular, it enables cells to rapidly manipulate protein production without new mRNA synthesis, processing, or export. Recent studies have enhanced our understanding of the translation initiation process and helped elucidate how modifications of the general translational machinery regulate gene-specific protein production.

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