Alcohol use and the risk of developing Alzheimer's disease - PubMed (original) (raw)

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Alcohol use and the risk of developing Alzheimer's disease

S L Tyas. Alcohol Res Health. 2001.

Abstract

Some of the detrimental effects of heavy alcohol use on brain function are similar to those observed with Alzheimer's disease (AD). Although alcohol use may be a risk factor for AD, it is difficult to study this relationship because of similarities between alcoholic dementia and AD and because standard diagnostic criteria for alcoholic dementia have not yet been developed. Similar biological mechanisms may be involved in the effects of AD and alcohol abuse on the brain. Epidemiologic studies have investigated the relationship between alcohol use and AD but have not provided strong evidence to suggest that alcohol use influences the risk of developing AD. Further research is needed before the effect of alcohol use on AD is understood fully.

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Figures

Compared with the brain of a normal elderly individual (Panel A), the wider grooves and narrower ridges of the brains in Panels B and C reflect the shrinkage of brain tissue seen in Alzheimer’s disease and alcoholism. SOURCE: Photographs in panels A and B courtesy of Sanders-Brown Center on Aging, University of Kentucky. Panel C originally appeared in Alcohol Health & Research World 19(4), 1995, p. 268.

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