Delta/Notch signaling promotes formation of zebrafish neural crest by repressing Neurogenin 1 function - PubMed (original) (raw)
Delta/Notch signaling promotes formation of zebrafish neural crest by repressing Neurogenin 1 function
Robert A Cornell et al. Development. 2002 Jun.
Erratum in
- Development 2002 Jul;129(13):3279
Abstract
In zebrafish, cells at the lateral edge of the neural plate become Rohon-Beard primary sensory neurons or neural crest. Delta/Notch signaling is required for neural crest formation. ngn1 is expressed in primary neurons; inhibiting Ngn1 activity prevents Rohon-Beard cell formation but not formation of other primary neurons. Reducing Ngn1 activity in embryos lacking Delta/Notch signaling restores neural crest formation, indicating Delta/Notch signaling inhibits neurogenesis without actively promoting neural crest. Ngn1 activity is also required for later development of dorsal root ganglion sensory neurons; however, Rohon-Beard neurons and dorsal root ganglion neurons are not necessarily derived from the same precursor cell. We propose that temporally distinct episodes of Ngn1 activity in the same precursor population specify these two different types of sensory neurons.
Similar articles
- dlx3b and dlx4b function in the development of Rohon-Beard sensory neurons and trigeminal placode in the zebrafish neurula.
Kaji T, Artinger KB. Kaji T, et al. Dev Biol. 2004 Dec 15;276(2):523-40. doi: 10.1016/j.ydbio.2004.09.020. Dev Biol. 2004. PMID: 15581883 Free PMC article. - Zebrafish narrowminded suggests a genetic link between formation of neural crest and primary sensory neurons.
Artinger KB, Chitnis AB, Mercola M, Driever W. Artinger KB, et al. Development. 1999 Sep;126(18):3969-79. doi: 10.1242/dev.126.18.3969. Development. 1999. PMID: 10457007 Free PMC article. - Zebrafish narrowminded disrupts the transcription factor prdm1 and is required for neural crest and sensory neuron specification.
Hernandez-Lagunas L, Choi IF, Kaji T, Simpson P, Hershey C, Zhou Y, Zon L, Mercola M, Artinger KB. Hernandez-Lagunas L, et al. Dev Biol. 2005 Feb 15;278(2):347-57. doi: 10.1016/j.ydbio.2004.11.014. Dev Biol. 2005. PMID: 15680355 Free PMC article. - Extracellular signals, cell interactions and transcription factors involved in the induction of the neural crest cells.
Aybar MJ, Glavic A, Mayor R. Aybar MJ, et al. Biol Res. 2002;35(2):267-75. doi: 10.4067/s0716-97602002000200018. Biol Res. 2002. PMID: 12415744 Review. - Cell Fate Decisions in the Neural Crest, from Pigment Cell to Neural Development.
Dawes JHP, Kelsh RN. Dawes JHP, et al. Int J Mol Sci. 2021 Dec 16;22(24):13531. doi: 10.3390/ijms222413531. Int J Mol Sci. 2021. PMID: 34948326 Free PMC article. Review.
Cited by
- Damage-induced basal epithelial cell migration modulates the spatial organization of redox signaling and sensory neuron regeneration.
Fister AM, Horn A, Lasarev MR, Huttenlocher A. Fister AM, et al. Elife. 2024 Aug 29;13:RP94995. doi: 10.7554/eLife.94995. Elife. 2024. PMID: 39207919 Free PMC article. - Rohon-beard neurons do not succumb to programmed cell death during zebrafish development.
Liu KE, Kucenas S. Liu KE, et al. Dev Biol. 2024 Nov;515:186-198. doi: 10.1016/j.ydbio.2024.06.020. Epub 2024 Jun 27. Dev Biol. 2024. PMID: 38944329 - Dolutegravir and Folic Acid Interaction during Neural System Development in Zebrafish Embryos.
Zizioli D, Quiros-Roldan E, Ferretti S, Mignani L, Tiecco G, Monti E, Castelli F, Zanella I. Zizioli D, et al. Int J Mol Sci. 2024 Apr 24;25(9):4640. doi: 10.3390/ijms25094640. Int J Mol Sci. 2024. PMID: 38731859 Free PMC article. - Osteoblasts pattern endothelium and somatosensory axons during zebrafish caudal fin organogenesis.
Bump RG, Goo CEA, Horton EC, Rasmussen JP. Bump RG, et al. Development. 2022 Feb 1;149(3):dev200172. doi: 10.1242/dev.200172. Epub 2022 Feb 7. Development. 2022. PMID: 35129199 Free PMC article. - Single-cell RNA analysis identifies pre-migratory neural crest cells expressing markers of differentiated derivatives.
Lencer E, Prekeris R, Artinger KB. Lencer E, et al. Elife. 2021 Aug 16;10:e66078. doi: 10.7554/eLife.66078. Elife. 2021. PMID: 34397384 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases