Community-acquired methicillin-resistant Staphylococcus aureus, Finland - PubMed (original) (raw)

Community-acquired methicillin-resistant Staphylococcus aureus, Finland

Saara Salmenlinna et al. Emerg Infect Dis. 2002 Jun.

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is no longer only hospital acquired. MRSA is defined as community acquired if the MRSA-positive specimen was obtained outside hospital settings or within 2 days of hospital admission, and if it was from a person who had not been hospitalized within 2 years before the date of MRSA isolation. To estimate the proportion of community-acquired MRSA, we analyzed previous hospitalizations for all MRSA-positive persons in Finland from 1997 to 1999 by using data from the National Hospital Discharge Register. Of 526 MRSA-positive persons, 21% had community-acquired MRSA. Three MRSA strains identified by phage typing, pulsed-field gel electrophoresis, and ribotyping were associated with community acquisition. None of the strains were multiresistant, and all showed an mec hypervariable region hybridization pattern A (HVR type A). None of the epidemic multiresistant hospital strains were prevalent in nonhospitalized persons. Our population-based data suggest that community-acquired MRSA may also arise de novo, through horizontal acquisition of the mecA gene.

PubMed Disclaimer

Figures

Figure

Figure

Pulsed-field gel electrophoresis (PFGE) profiles of the 14 most common methicillin-resistant Staphylococcus aureus (MRSA) strain types identified, Finland, 1997–1999. Lanes 1, 9, 17: S. aureus NCTC 8325 (molecular weight marker); lanes 2–4: strain types associated with community acquisition (Mikkeli clone, E22, E31); lane 5: E1; lane 6: E24; lane 7: E5; lane 8: Kemi clone; lane 10: E27; lane 11: UK EMRSA-15; lane 12: E19; lane 13: Pori clone; lane 14: E20; lane 15: Iberian clone; and lane 16: O25.

Similar articles

Cited by

References

    1. Herold B, Immergluck L, Maranan M, Lauderdale D, Gaskin R, Boyle-Vavra S, et al. Community-acquired methicillin-resistant Staphylococcus aureus in children with no identified predisposing risk. JAMA. 1998;279:593–8. 10.1001/jama.279.8.593 - DOI - PubMed
    1. Lindenmayer JM, Schoenfeld S, O’Grady R, Carney JK. Methicillin-resistant Staphylococcus aureus in a high school wrestling team and the surrounding community. Arch Intern Med. 1998;158:895–9. 10.1001/archinte.158.8.895 - DOI - PubMed
    1. Gorak E, Yamada S, Brown J. Community-acquired methicillin-resistant Staphylococcus aureus in hospitalized adults and children without known risk factors. Clin Infect Dis. 1999;29:797–800. 10.1086/520437 - DOI - PubMed
    1. L’Hériteau F, Lucet J-C, Scanvic A, Bouvet E. Community-acquired methicillin-resistant Staphylococcus aureus and familial transmission. JAMA. 1999;282:1038–9. 10.1001/jama.282.11.1038 - DOI - PubMed
    1. Shopsin B, Mathema B, Martinez J, Ha E, Campo ML, Fierman A, et al. Prevalence of methicillin-resistant Staphylococcus aureus in the community. J Infect Dis. 2000;182:359–62. 10.1086/315695 - DOI - PubMed

MeSH terms

Substances

LinkOut - more resources