The relation of body mass index, cardiorespiratory fitness, and all-cause mortality in women - PubMed (original) (raw)
The relation of body mass index, cardiorespiratory fitness, and all-cause mortality in women
Stephen W Farrell et al. Obes Res. 2002 Jun.
Free article
Abstract
Objective: To examine the relation of body mass index (BMI), cardiorespiratory fitness (CRF), and all-cause mortality in women.
Research methods and procedures: A cohort of women (42.9 +/- 10.4 years) was assessed for CRF, height, and weight. Participants were divided into three BMI categories (normal, overweight, and obese) and three CRF categories (low, moderate, and high). After adjustment for age, smoking, and baseline health status, the relative risk (RR) of all-cause mortality was determined for each group. Further multivariate analyses were performed to examine the contribution of each predictor (e.g., age, BMI, CRF, smoking status, and baseline health status) on all-cause mortality while controlling for all other predictors.
Results: During follow-up (113,145 woman-years), 195 deaths from all causes occurred. Compared with normal weight (RR = 1.0), overweight (RR = 0.92) and obesity (RR = 1.58) did not significantly increase all-cause mortality risk. Compared with low CRF (RR = 1.0), moderate (RR = 0.48) and high (RR = 0.57) CRF were associated significantly with lower mortality risk (p = 0.002). In multivariate analyses, moderate (RR = 0.49) and high (RR = 0.57) CRF were strongly associated with decreased mortality relative to low CRF (p = 0.003). Compared with normal weight (RR = 1.0), overweight (RR = 0.84) and obesity (RR = 1.21) were not significantly associated with all-cause mortality.
Discussion: Low CRF in women was an important predictor of all-cause mortality. BMI, as a predictor of all-cause mortality risk in women, may be misleading unless CRF is also considered.
Similar articles
- Cardiorespiratory fitness, different measures of adiposity, and cancer mortality in men.
Farrell SW, Cortese GM, LaMonte MJ, Blair SN. Farrell SW, et al. Obesity (Silver Spring). 2007 Dec;15(12):3140-9. doi: 10.1038/oby.2007.374. Obesity (Silver Spring). 2007. PMID: 18198325 - Cardiorespiratory fitness, different measures of adiposity, and total cancer mortality in women.
Farrell SW, Finley CE, McAuley PA, Frierson GM. Farrell SW, et al. Obesity (Silver Spring). 2011 Nov;19(11):2261-7. doi: 10.1038/oby.2010.345. Epub 2011 Feb 3. Obesity (Silver Spring). 2011. PMID: 21293448 - [A prospective study on body mass index and mortality].
Zhao L, Zhou B, Wu Y, Li Y, Yang J. Zhao L, et al. Zhonghua Liu Xing Bing Xue Za Zhi. 2002 Feb;23(1):24-7. Zhonghua Liu Xing Bing Xue Za Zhi. 2002. PMID: 12015104 Chinese. - Contribution of cardiorespiratory fitness to the obesity paradox.
McAuley PA, Beavers KM. McAuley PA, et al. Prog Cardiovasc Dis. 2014 Jan-Feb;56(4):434-40. doi: 10.1016/j.pcad.2013.09.006. Epub 2013 Oct 11. Prog Cardiovasc Dis. 2014. PMID: 24438735 Review. - Fitness vs. fatness on all-cause mortality: a meta-analysis.
Barry VW, Baruth M, Beets MW, Durstine JL, Liu J, Blair SN. Barry VW, et al. Prog Cardiovasc Dis. 2014 Jan-Feb;56(4):382-90. doi: 10.1016/j.pcad.2013.09.002. Epub 2013 Oct 11. Prog Cardiovasc Dis. 2014. PMID: 24438729 Review.
Cited by
- Physical Activity, Cardiorespiratory Fitness, and the Obesity Paradox with Consideration for Racial and/or Ethnic Differences: A Broad Review and Call to Action.
Sparks JR, Wang X, Lavie CJ, Sui X. Sparks JR, et al. Rev Cardiovasc Med. 2024 Aug 19;25(8):291. doi: 10.31083/j.rcm2508291. eCollection 2024 Aug. Rev Cardiovasc Med. 2024. PMID: 39228496 Free PMC article. Review. - CT and MR utilization and morbidity metrics across Body Mass Index.
Dawod M, Nagib P, Zaki J, Prevedello LM, Ajam AA, Nguyen XV. Dawod M, et al. PLoS One. 2024 Jun 28;19(6):e0306087. doi: 10.1371/journal.pone.0306087. eCollection 2024. PLoS One. 2024. PMID: 38941332 Free PMC article. - Influence of exercise type and duration on cardiorespiratory fitness and muscular strength in post-menopausal women: a systematic review and meta-analysis.
Khalafi M, Sakhaei MH, Habibi Maleki A, Rosenkranz SK, Pourvaghar MJ, Fang Y, Korivi M. Khalafi M, et al. Front Cardiovasc Med. 2023 May 9;10:1190187. doi: 10.3389/fcvm.2023.1190187. eCollection 2023. Front Cardiovasc Med. 2023. PMID: 37229231 Free PMC article. Review. - Validation, Recalibration, and Predictive Accuracy of Published V̇O 2max Prediction Equations for Adults Ages 50-96 Yr.
Schumacher BT, DI C, Bellettiere J, Lamonte MJ, Simonsick EM, Parada H Jr, Hooker SP, Lacroix AZ. Schumacher BT, et al. Med Sci Sports Exerc. 2023 Feb 1;55(2):322-332. doi: 10.1249/MSS.0000000000003033. Epub 2022 Sep 3. Med Sci Sports Exerc. 2023. PMID: 36069964 Free PMC article. - The State of Obesity in Kansas: A Community Based Approach to Chronic Care Management.
Bretches MP, Schwasinger-Schmidt TE. Bretches MP, et al. Kans J Med. 2021 Jan 21;14:21-28. doi: 10.17161/kjm.vol1413751. eCollection 2021. Kans J Med. 2021. PMID: 33643525 Free PMC article. Review. No abstract available.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical