RIM1: an edge for presynaptic plasticity - PubMed (original) (raw)
Review
RIM1: an edge for presynaptic plasticity
György Lonart. Trends Neurosci. 2002 Jul.
Abstract
Pioneering work suggests that a synaptic active zone protein, RIM1, regulates both short- and long-term glutamatergic presynaptic plasticity at certain synapses. In short-term plasticity, RIM1 accelerates the priming of synaptic vesicles for fusion; by contrast, in long-term potentiation of mossy fiber synapses in the hippocampal CA3 region, phosphorylated RIM1 acts through an unknown molecular pathway to enhance release of the excitatory neurotransmitter glutamate.
Similar articles
- Synaptic vesicle dynamics in the mossy fiber-CA3 presynaptic terminals of mouse hippocampus.
Suyama S, Hikima T, Sakagami H, Ishizuka T, Yawo H. Suyama S, et al. Neurosci Res. 2007 Dec;59(4):481-90. doi: 10.1016/j.neures.2007.08.019. Epub 2007 Sep 12. Neurosci Res. 2007. PMID: 17933408 - Active zones for presynaptic plasticity in the brain.
García-Junco-Clemente P, Linares-Clemente P, Fernández-Chacón R. García-Junco-Clemente P, et al. Mol Psychiatry. 2005 Feb;10(2):185-200; image 131. doi: 10.1038/sj.mp.4001628. Mol Psychiatry. 2005. PMID: 15630409 Review. - Structural plasticity of hippocampal mossy fiber synapses as revealed by high-pressure freezing.
Zhao S, Studer D, Chai X, Graber W, Brose N, Nestel S, Young C, Rodriguez EP, Saetzler K, Frotscher M. Zhao S, et al. J Comp Neurol. 2012 Aug 1;520(11):2340-51. doi: 10.1002/cne.23040. J Comp Neurol. 2012. PMID: 22237743 - Snares and Munc18 in synaptic vesicle fusion.
Rizo J, Südhof TC. Rizo J, et al. Nat Rev Neurosci. 2002 Aug;3(8):641-53. doi: 10.1038/nrn898. Nat Rev Neurosci. 2002. PMID: 12154365 Review. No abstract available. - Modulation of hippocampal synaptic transmission and plasticity by neurotrophins.
Lu B, Gottschalk W. Lu B, et al. Prog Brain Res. 2000;128:231-41. doi: 10.1016/S0079-6123(00)28020-5. Prog Brain Res. 2000. PMID: 11105682 Review. No abstract available.
Cited by
- Changes in Gene Expression of Whiteflies, Bemisia tabaci MED Feeding on Tomato Plants Infected by One of the Criniviruses, Tomato Chlorosis Virus through Transcriptome Analysis.
Zhao J, Sun X, Dai H, Zhang X, Zhang D, Zhu X. Zhao J, et al. Int J Genomics. 2023 May 22;2023:3807812. doi: 10.1155/2023/3807812. eCollection 2023. Int J Genomics. 2023. PMID: 37261104 Free PMC article. - Shaping Neuronal Network Activity by Presynaptic Mechanisms.
Lavi A, Perez O, Ashery U. Lavi A, et al. PLoS Comput Biol. 2015 Sep 15;11(9):e1004438. doi: 10.1371/journal.pcbi.1004438. eCollection 2015 Sep. PLoS Comput Biol. 2015. PMID: 26372048 Free PMC article. - Transcriptional evidence for the role of chronic venlafaxine treatment in neurotrophic signaling and neuroplasticity including also Glutamatergic [corrected] - and insulin-mediated neuronal processes.
Tamási V, Petschner P, Adori C, Kirilly E, Ando RD, Tothfalusi L, Juhasz G, Bagdy G. Tamási V, et al. PLoS One. 2014 Nov 25;9(11):e113662. doi: 10.1371/journal.pone.0113662. eCollection 2014. PLoS One. 2014. PMID: 25423262 Free PMC article. - Association between regulating synaptic membrane exocytosis 2 gene polymorphisms and degenerative lumbar scoliosis.
Kim KT, Lee JS, Lee BW, Seok H, Jeon HS, Kim JH, Chung JH. Kim KT, et al. Biomed Rep. 2013 Jul;1(4):619-623. doi: 10.3892/br.2013.101. Epub 2013 May 9. Biomed Rep. 2013. PMID: 24648997 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Miscellaneous