Molecular biology. Chromatin higher order folding--wrapping up transcription - PubMed (original) (raw)
Review
. 2002 Sep 13;297(5588):1824-7.
doi: 10.1126/science.1074200.
Affiliations
- PMID: 12228709
- DOI: 10.1126/science.1074200
Review
Molecular biology. Chromatin higher order folding--wrapping up transcription
Peter J Horn et al. Science. 2002.
Abstract
Eukaryotic genomes are organized into condensed, heterogeneous chromatin fibers throughout much of the cell cycle. Here we describe recent studies indicating that even transcriptionally active loci may be encompassed within 80- to 100-nanometer-thick chromonema fibers. These studies suggest that chromatin higher order folding may be a key feature of eukaryotic transcriptional control. We also discuss evidence suggesting that adenosine-5'-triphosphate-dependent chromatin-remodeling enzymes and histone-modifying enzymes may regulate transcription by controlling the extent and dynamics of chromatin higher order folding.
Similar articles
- Changing chromatin from the inside.
Hayes JJ. Hayes JJ. Nat Struct Biol. 2002 Mar;9(3):161-3. doi: 10.1038/nsb0302-161. Nat Struct Biol. 2002. PMID: 11875512 No abstract available. - Remodeling chromatin structures for transcription: what happens to the histones?
Steger DJ, Workman JL. Steger DJ, et al. Bioessays. 1996 Nov;18(11):875-84. doi: 10.1002/bies.950181106. Bioessays. 1996. PMID: 8939065 Review. - Molecular biology. A higher order of silence.
Mohd-Sarip A, Verrijzer CP. Mohd-Sarip A, et al. Science. 2004 Nov 26;306(5701):1484-5. doi: 10.1126/science.1106767. Science. 2004. PMID: 15567842 No abstract available. - ATP-dependent chromatin remodeling.
Smith CL, Peterson CL. Smith CL, et al. Curr Top Dev Biol. 2005;65:115-48. doi: 10.1016/S0070-2153(04)65004-6. Curr Top Dev Biol. 2005. PMID: 15642381 Review. - Influence of linker histone H1 on chromatin remodeling.
Hill DA. Hill DA. Biochem Cell Biol. 2001;79(3):317-24. Biochem Cell Biol. 2001. PMID: 11467745 Review.
Cited by
- ATP-Dependent Chromatin Remodellers in Inner Ear Development.
Chohra I, Chung K, Giri S, Malgrange B. Chohra I, et al. Cells. 2023 Feb 7;12(4):532. doi: 10.3390/cells12040532. Cells. 2023. PMID: 36831199 Free PMC article. Review. - Stochastic chromatin packing of 3D mitotic chromosomes revealed by coherent X-rays.
Sung D, Lim C, Takagi M, Jung C, Lee H, Cho DH, Shin JY, Ahn K, Hwang J, Nam D, Kohmura Y, Ishikawa T, Noh DY, Imamoto N, Jeon JH, Song C. Sung D, et al. Proc Natl Acad Sci U S A. 2021 Nov 16;118(46):e2109921118. doi: 10.1073/pnas.2109921118. Proc Natl Acad Sci U S A. 2021. PMID: 34750262 Free PMC article. - Remodeling the chromatin landscape in T lymphocytes by a division of labor among transcription factors.
Vahedi G. Vahedi G. Immunol Rev. 2021 Mar;300(1):167-180. doi: 10.1111/imr.12942. Epub 2021 Jan 15. Immunol Rev. 2021. PMID: 33452686 Free PMC article. Review. - Systemic HDAC3 inhibition ameliorates impairments in synaptic plasticity caused by simulated galactic cosmic radiation exposure in male mice.
Keiser AA, Kramár EA, Dong T, Shanur S, Pirodan M, Ru N, Acharya MM, Baulch JE, Limoli CL, Wood MA. Keiser AA, et al. Neurobiol Learn Mem. 2021 Feb;178:107367. doi: 10.1016/j.nlm.2020.107367. Epub 2020 Dec 24. Neurobiol Learn Mem. 2021. PMID: 33359392 Free PMC article. - Opioid-induced structural and functional plasticity of medium-spiny neurons in the nucleus accumbens.
Thompson BL, Oscar-Berman M, Kaplan GB. Thompson BL, et al. Neurosci Biobehav Rev. 2021 Jan;120:417-430. doi: 10.1016/j.neubiorev.2020.10.015. Epub 2020 Nov 2. Neurosci Biobehav Rev. 2021. PMID: 33152423 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases