Molecular biology. Chromatin higher order folding--wrapping up transcription - PubMed (original) (raw)
Review
. 2002 Sep 13;297(5588):1824-7.
doi: 10.1126/science.1074200.
Affiliations
- PMID: 12228709
- DOI: 10.1126/science.1074200
Review
Molecular biology. Chromatin higher order folding--wrapping up transcription
Peter J Horn et al. Science. 2002.
Abstract
Eukaryotic genomes are organized into condensed, heterogeneous chromatin fibers throughout much of the cell cycle. Here we describe recent studies indicating that even transcriptionally active loci may be encompassed within 80- to 100-nanometer-thick chromonema fibers. These studies suggest that chromatin higher order folding may be a key feature of eukaryotic transcriptional control. We also discuss evidence suggesting that adenosine-5'-triphosphate-dependent chromatin-remodeling enzymes and histone-modifying enzymes may regulate transcription by controlling the extent and dynamics of chromatin higher order folding.
Similar articles
- Changing chromatin from the inside.
Hayes JJ. Hayes JJ. Nat Struct Biol. 2002 Mar;9(3):161-3. doi: 10.1038/nsb0302-161. Nat Struct Biol. 2002. PMID: 11875512 No abstract available. - Remodeling chromatin structures for transcription: what happens to the histones?
Steger DJ, Workman JL. Steger DJ, et al. Bioessays. 1996 Nov;18(11):875-84. doi: 10.1002/bies.950181106. Bioessays. 1996. PMID: 8939065 Review. - Molecular biology. A higher order of silence.
Mohd-Sarip A, Verrijzer CP. Mohd-Sarip A, et al. Science. 2004 Nov 26;306(5701):1484-5. doi: 10.1126/science.1106767. Science. 2004. PMID: 15567842 No abstract available. - ATP-dependent chromatin remodeling.
Smith CL, Peterson CL. Smith CL, et al. Curr Top Dev Biol. 2005;65:115-48. doi: 10.1016/S0070-2153(04)65004-6. Curr Top Dev Biol. 2005. PMID: 15642381 Review. - Influence of linker histone H1 on chromatin remodeling.
Hill DA. Hill DA. Biochem Cell Biol. 2001;79(3):317-24. Biochem Cell Biol. 2001. PMID: 11467745 Review.
Cited by
- Atomic Force Microscopy Characterization of Reconstituted Protein-DNA Complexes.
Cajili MKM, Prieto EI. Cajili MKM, et al. Methods Mol Biol. 2024;2819:279-295. doi: 10.1007/978-1-0716-3930-6_14. Methods Mol Biol. 2024. PMID: 39028512 - Reduction of nucleosome assembly during new DNA synthesis impairs both major pathways of double-strand break repair.
Lewis LK, Karthikeyan G, Cassiano J, Resnick MA. Lewis LK, et al. Nucleic Acids Res. 2005 Sep 1;33(15):4928-39. doi: 10.1093/nar/gki806. Print 2005. Nucleic Acids Res. 2005. PMID: 16141196 Free PMC article. - Examining the contribution of histone modification to sex differences in learning and memory.
Keiser AA, Wood MA. Keiser AA, et al. Learn Mem. 2019 Aug 15;26(9):318-331. doi: 10.1101/lm.048850.118. Print 2019 Sep. Learn Mem. 2019. PMID: 31416905 Free PMC article. Review. - Chromatin remodeling by nuclear receptors.
Hebbar PB, Archer TK. Hebbar PB, et al. Chromosoma. 2003 May;111(8):495-504. doi: 10.1007/s00412-003-0232-x. Epub 2003 Feb 26. Chromosoma. 2003. PMID: 12743713 Review. - Nitric oxide: perspectives and emerging studies of a well known cytotoxin.
Paradise WA, Vesper BJ, Goel A, Waltonen JD, Altman KW, Haines GK, Radosevich JA. Paradise WA, et al. Int J Mol Sci. 2010 Jul 16;11(7):2715-45. doi: 10.3390/ijms11072715. Int J Mol Sci. 2010. PMID: 20717533 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Molecular Biology Databases