Integrin signaling: it's where the action is - PubMed (original) (raw)
Review
Integrin signaling: it's where the action is
Caroline H Damsky et al. Curr Opin Cell Biol. 2002 Oct.
Abstract
Recent advances highlight a critical role for integrin receptors for extracellular matrix in determining where in cells critical signals are transduced. Integrins are shown to activate signaling intermediates at specific surface membrane locations, to promote nuclear translocation of factors that activate gene transcription, and to recruit and augment the signaling power of receptors for growth factors.
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