Increased risk of childhood type 1 diabetes in children born after 1985 - PubMed (original) (raw)
Increased risk of childhood type 1 diabetes in children born after 1985
Jannet Svensson et al. Diabetes Care. 2002 Dec.
Abstract
Objective: The incidence rate of childhood type 1 diabetes is thought to be increasing; however, Danish studies have not confirmed this. Using a national diabetes register initiated in 1996 and two previous regional incidence studies, we studied the age-specific incidence of type 1 diabetes over 30 years. Here, we describe the incidence rates of type 1 diabetes in Danish children from 1996 to 2000 and evaluate trends in age-specific incidence rates from 1970 to 2000.
Research design and methods: A nationwide registration of all newly diagnosed cases of type 1 diabetes among children under the age of 15 years was established in Denmark in 1996. Incidence rates of type 1 diabetes in Denmark were obtained from this register. Age-specific incidence rates were compared with data collected from 1970 to 1976 and from 1980 to 1984, both population-based studies using existing national routine registration of hospitalizations within the survey areas. Population data were obtained from Statistics Denmark.
Results: During the study period, 1,421 Danish children developed type 1 diabetes before the age of 15 years. The incidence rates by age-groups were: 12.7, 19.4, and 26.3 for the 0-4, 5-9, and 10-14 years age-groups, respectively, and 19.5 for the 0-14 years age-group per 100,000 in the period 1996-2000. An age-period-cohort analysis showed a modest drift effect (yearly increase) of 1.2% (0.7-1.8) from 1970 to 2000, and a significant birth cohort effect with an increased risk for children born after 1985 was observed.
Conclusions: The incidence rate of type 1 diabetes is rising in children living in Denmark. The steep increase in the youngest age-group was explained by the increased risk for cohorts born at the beginning of the 1980s.
Similar articles
- Infant Growth and Risk of Childhood-Onset Type 1 Diabetes in Children From 2 Scandinavian Birth Cohorts.
Magnus MC, Olsen SF, Granström C, Joner G, Skrivarhaug T, Svensson J, Johannesen J, Njølstad P, Magnus P, Størdal K, Stene LC. Magnus MC, et al. JAMA Pediatr. 2015 Dec;169(12):e153759. doi: 10.1001/jamapediatrics.2015.3759. Epub 2015 Dec 7. JAMA Pediatr. 2015. PMID: 26642117 - Increased risk of precocious puberty in internationally adopted children in Denmark.
Teilmann G, Pedersen CB, Skakkebaek NE, Jensen TK. Teilmann G, et al. Pediatrics. 2006 Aug;118(2):e391-9. doi: 10.1542/peds.2005-2939. Pediatrics. 2006. PMID: 16882780 - [Incidence of juvenile-onset diabetes in Denmark. A prospective registration in the counties of Fyn, Ribe, Sønderjylland and Vejle].
Svendsen AJ, Kreutzfeld JC, Lund EB, Kyvik KO, Green A. Svendsen AJ, et al. Ugeskr Laeger. 1997 Feb 24;159(9):1257-60. Ugeskr Laeger. 1997. PMID: 9072870 Danish. - ["Constantly rising or peaks and plateaus?" Incidence of childhood type 1 diabetes in Hungary (1989-2009)].
Gyürüs E, Patterson C, Soltész G. Gyürüs E, et al. Orv Hetil. 2011 Oct 16;152(42):1692-7. doi: 10.1556/OH.2011.29210. Orv Hetil. 2011. PMID: 21979222 Review. Hungarian. - Mortality and morbidity in patients with osteogenesis imperfecta in Denmark.
Folkestad L. Folkestad L. Dan Med J. 2018 Apr;65(4):B5454. Dan Med J. 2018. PMID: 29619932 Review.
Cited by
- Long-term trends in the burden of inflammatory bowel disease in China over three decades: A joinpoint regression and age-period-cohort analysis based on GBD 2019.
Zhang Y, Liu J, Han X, Jiang H, Zhang L, Hu J, Shi L, Li J. Zhang Y, et al. Front Public Health. 2022 Sep 7;10:994619. doi: 10.3389/fpubh.2022.994619. eCollection 2022. Front Public Health. 2022. PMID: 36159285 Free PMC article. - Assessing Health Consequences of Vitamin D Fortification Utilizing a Societal Experiment Design: Methodological Lessons Learned from the D-Tect Project.
Händel MN, Jacobsen R, Thorsteinsdottir F, Keller AC, Stougaard M, Jensen CB, Moos C, Duus KS, Jensen A, Schiøler Kesmodel U, Abrahamsen B, Heitmann BL. Händel MN, et al. Int J Environ Res Public Health. 2021 Jul 31;18(15):8136. doi: 10.3390/ijerph18158136. Int J Environ Res Public Health. 2021. PMID: 34360427 Free PMC article. Review. - Insufficient Sun Exposure Has Become a Real Public Health Problem.
Alfredsson L, Armstrong BK, Butterfield DA, Chowdhury R, de Gruijl FR, Feelisch M, Garland CF, Hart PH, Hoel DG, Jacobsen R, Lindqvist PG, Llewellyn DJ, Tiemeier H, Weller RB, Young AR. Alfredsson L, et al. Int J Environ Res Public Health. 2020 Jul 13;17(14):5014. doi: 10.3390/ijerph17145014. Int J Environ Res Public Health. 2020. PMID: 32668607 Free PMC article. Review. - Prevalence and incidence of type 1 diabetes in the world: a systematic review and meta-analysis.
Mobasseri M, Shirmohammadi M, Amiri T, Vahed N, Hosseini Fard H, Ghojazadeh M. Mobasseri M, et al. Health Promot Perspect. 2020 Mar 30;10(2):98-115. doi: 10.34172/hpp.2020.18. eCollection 2020. Health Promot Perspect. 2020. PMID: 32296622 Free PMC article. Review. - Is the incidence of type 1 diabetes in children and adolescents stabilising? The first 6 years of a National Register.
Roche EF, McKenna AM, Ryder KJ, Brennan AA, O'Regan M, Hoey HM. Roche EF, et al. Eur J Pediatr. 2016 Dec;175(12):1913-1919. doi: 10.1007/s00431-016-2787-6. Epub 2016 Sep 22. Eur J Pediatr. 2016. PMID: 27659662
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Medical