Rethinking feelings: an FMRI study of the cognitive regulation of emotion - PubMed (original) (raw)
Rethinking feelings: an FMRI study of the cognitive regulation of emotion
Kevin N Ochsner et al. J Cogn Neurosci. 2002.
Abstract
The ability to cognitively regulate emotional responses to aversive events is important for mental and physical health. Little is known, however, about neural bases of the cognitive control of emotion. The present study employed functional magnetic resonance imaging to examine the neural systems used to reappraise highly negative scenes in unemotional terms. Reappraisal of highly negative scenes reduced subjective experience of negative affect. Neural correlates of reappraisal were increased activation of the lateral and medial prefrontal regions and decreased activation of the amygdala and medial orbito-frontal cortex. These findings support the hypothesis that prefrontal cortex is involved in constructing reappraisal strategies that can modulate activity in multiple emotion-processing systems.
Similar articles
- For better or for worse: neural systems supporting the cognitive down- and up-regulation of negative emotion.
Ochsner KN, Ray RD, Cooper JC, Robertson ER, Chopra S, Gabrieli JD, Gross JJ. Ochsner KN, et al. Neuroimage. 2004 Oct;23(2):483-99. doi: 10.1016/j.neuroimage.2004.06.030. Neuroimage. 2004. PMID: 15488398 - Neural correlates of positive and negative emotion regulation.
Kim SH, Hamann S. Kim SH, et al. J Cogn Neurosci. 2007 May;19(5):776-98. doi: 10.1162/jocn.2007.19.5.776. J Cogn Neurosci. 2007. PMID: 17488204 - Neural substrates for voluntary suppression of negative affect: a functional magnetic resonance imaging study.
Phan KL, Fitzgerald DA, Nathan PJ, Moore GJ, Uhde TW, Tancer ME. Phan KL, et al. Biol Psychiatry. 2005 Feb 1;57(3):210-9. doi: 10.1016/j.biopsych.2004.10.030. Biol Psychiatry. 2005. PMID: 15691521 - Prefrontal involvement in the regulation of emotion: convergence of rat and human studies.
Quirk GJ, Beer JS. Quirk GJ, et al. Curr Opin Neurobiol. 2006 Dec;16(6):723-7. doi: 10.1016/j.conb.2006.07.004. Epub 2006 Nov 3. Curr Opin Neurobiol. 2006. PMID: 17084617 Review. - [Relationship between the amygdala activity and emotion/stress responses as revealed by fMRI and genetic analysis].
Iidaka T. Iidaka T. Nihon Shinkei Seishin Yakurigaku Zasshi. 2008 Nov;28(5-6):185-8. Nihon Shinkei Seishin Yakurigaku Zasshi. 2008. PMID: 19108504 Review. Japanese.
Cited by
- Evaluating the Effectiveness of a School-Based Cognitive Behavioural Therapy Intervention for Anxiety in Adolescents Diagnosed with Autism Spectrum Disorder.
Luxford S, Hadwin JA, Kovshoff H. Luxford S, et al. J Autism Dev Disord. 2017 Dec;47(12):3896-3908. doi: 10.1007/s10803-016-2857-7. J Autism Dev Disord. 2017. PMID: 27440250 Free PMC article. Clinical Trial. - Moving beyond Mindfulness: Defining Equanimity as an Outcome Measure in Meditation and Contemplative Research.
Desbordes G, Gard T, Hoge EA, Hölzel BK, Kerr C, Lazar SW, Olendzki A, Vago DR. Desbordes G, et al. Mindfulness (N Y). 2014 Jan 21;2014(January):356-72. doi: 10.1007/s12671-013-0269-8. Mindfulness (N Y). 2014. PMID: 25750687 Free PMC article. - The longitudinal trajectory of emotion regulation and associated neural activity in patients with bipolar disorder: A prospective fMRI study.
Kjaerstad HL, de Siqueira Rotenberg L, Knudsen GM, Vinberg M, Kessing LV, Macoveanu J, Lafer B, Miskowiak KW. Kjaerstad HL, et al. Acta Psychiatr Scand. 2022 Dec;146(6):568-582. doi: 10.1111/acps.13488. Epub 2022 Aug 31. Acta Psychiatr Scand. 2022. PMID: 36054343 Free PMC article. - Sex-related differences in brain dynamism at rest as neural correlates of positive and negative valence system constructs.
de Lacy N, Kutz JN, Calhoun VD. de Lacy N, et al. Cogn Neurosci. 2021 Jul-Oct;12(3-4):131-154. doi: 10.1080/17588928.2020.1793752. Epub 2020 Jul 26. Cogn Neurosci. 2021. PMID: 32715898 Free PMC article. - Effects of mindful-attention and compassion meditation training on amygdala response to emotional stimuli in an ordinary, non-meditative state.
Desbordes G, Negi LT, Pace TW, Wallace BA, Raison CL, Schwartz EL. Desbordes G, et al. Front Hum Neurosci. 2012 Nov 1;6:292. doi: 10.3389/fnhum.2012.00292. eCollection 2012. Front Hum Neurosci. 2012. PMID: 23125828 Free PMC article.
Publication types
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources
Medical