AMP-activated protein kinase, super metabolic regulator - PubMed (original) (raw)
Review
. 2003 Feb;31(Pt 1):162-8.
doi: 10.1042/bst0310162.
D Stapleton, D J Campbell, Z-P Chen, S Murthy, M Walter, A Gupta, J J Adams, F Katsis, B van Denderen, I G Jennings, T Iseli, B J Michell, L A Witters
Affiliations
- PMID: 12546677
- DOI: 10.1042/bst0310162
Review
AMP-activated protein kinase, super metabolic regulator
B E Kemp et al. Biochem Soc Trans. 2003 Feb.
Abstract
The AMP-activated protein kinase (AMPK) is a metabolic-stress-sensing protein kinase that regulates metabolism in response to energy demand and supply by directly phosphorylating rate-limiting enzymes in metabolic pathways as well as controlling gene expression.
Similar articles
- [Regulation of energy metabolism by AMPK: a novel therapeutic approach for the treatment of metabolic and cardiovascular diseases].
Foretz M, Taleux N, Guigas B, Horman S, Beauloye C, Andreelli F, Bertrand L, Viollet B. Foretz M, et al. Med Sci (Paris). 2006 Apr;22(4):381-8. doi: 10.1051/medsci/2006224381. Med Sci (Paris). 2006. PMID: 16597407 Review. French. - Targeting AMP-activated protein kinase as a novel therapeutic approach for the treatment of metabolic disorders.
Viollet B, Mounier R, Leclerc J, Yazigi A, Foretz M, Andreelli F. Viollet B, et al. Diabetes Metab. 2007 Dec;33(6):395-402. doi: 10.1016/j.diabet.2007.10.004. Epub 2007 Nov 7. Diabetes Metab. 2007. PMID: 17997341 Review. - Role of AMP-activated protein kinase in the control of appetite.
Kola B. Kola B. J Neuroendocrinol. 2008 Jul;20(7):942-51. doi: 10.1111/j.1365-2826.2008.01745.x. Epub 2008 Apr 28. J Neuroendocrinol. 2008. PMID: 18445126 Free PMC article. Review. - A molecular approach to the concerted action of kinases involved in energy homoeostasis.
Neumann D, Schlattner U, Wallimann T. Neumann D, et al. Biochem Soc Trans. 2003 Feb;31(Pt 1):169-74. doi: 10.1042/bst0310169. Biochem Soc Trans. 2003. PMID: 12546678 Review. - AMP-activated protein kinase regulation of fatty acid oxidation in the ischaemic heart.
Hopkins TA, Dyck JR, Lopaschuk GD. Hopkins TA, et al. Biochem Soc Trans. 2003 Feb;31(Pt 1):207-12. doi: 10.1042/bst0310207. Biochem Soc Trans. 2003. PMID: 12546686 Review.
Cited by
- CTRP13 Mitigates Endothelial Cell Ferroptosis via the AMPK/KLF4 Pathway: Implications for Atherosclerosis Protection.
Du J, Wu J, Zhang Y, Liu Q, Luo X, Huang X, Wang X, Yang F, Hou J. Du J, et al. Med Sci Monit. 2024 Jan 26;30:e942733. doi: 10.12659/MSM.942733. Med Sci Monit. 2024. PMID: 38273650 Free PMC article. - Targeting Mitochondrial ATP-Synthase: Evolving Role of Chromium as a Regulator of Carbohydrate and Fat Metabolism.
Mattos Pereira V, Nair S. Mattos Pereira V, et al. Biol Trace Elem Res. 2024 Apr;202(4):1318-1324. doi: 10.1007/s12011-023-04017-z. Epub 2023 Dec 22. Biol Trace Elem Res. 2024. PMID: 38133723 Review. - Cyanidin-3-O-glucoside protects the brain and improves cognitive function in APPswe/PS1ΔE9 transgenic mice model.
Baek H, Sanjay, Park M, Lee HJ. Baek H, et al. J Neuroinflammation. 2023 Nov 17;20(1):268. doi: 10.1186/s12974-023-02950-3. J Neuroinflammation. 2023. PMID: 37978414 Free PMC article. - High glucose-upregulated PD-L1 expression through RAS signaling-driven downregulation of PTRH1 leads to suppression of T cell cytotoxic function in tumor environment.
Gao C, Chen J, Bai J, Zhang H, Tao Y, Wu S, Li H, Wu H, Shen Q, Yin T. Gao C, et al. J Transl Med. 2023 Jul 11;21(1):461. doi: 10.1186/s12967-023-04302-4. J Transl Med. 2023. PMID: 37434177 Free PMC article. - Ethanol Extract of Rosa laevigata Michx. Fruit Inhibits Inflammatory Responses through NF-κB/MAPK Signaling Pathways via AMPK Activation in RAW 264.7 Macrophages.
Wu H, Lin T, Chen Y, Chen F, Zhang S, Pang H, Huang L, Yu C, Wang G, Wu C. Wu H, et al. Molecules. 2023 Mar 20;28(6):2813. doi: 10.3390/molecules28062813. Molecules. 2023. PMID: 36985786 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources