The t-SNARE syntaxin 4 is regulated during macrophage activation to function in membrane traffic and cytokine secretion - PubMed (original) (raw)

Patients and mice with deficiency in the SNARE protein SYNTAXIN-11 have a secondary B cell defect.

Kögl T, Chang HF, Staniek J, Chiang SCC, Thoulass G, Lao J, Weißert K, Dettmer-Monaco V, Geiger K, Manna PT, Beziat V, Momenilandi M, Tu SM, Keppler SJ, Pattu V, Wolf P, Kupferschmid L, Tholen S, Covill LE, Ebert K, Straub T, Groß M, Gather R, Engel H, Salzer U, Schell C, Maier S, Lehmberg K, Cornu TI, Pircher H, Shahrooei M, Parvaneh N, Elling R, Rizzi M, Bryceson YT, Ehl S, Aichele P, Ammann S. Kögl T, et al. J Exp Med. 2024 Jul 1;221(7):e20221122. doi: 10.1084/jem.20221122. Epub 2024 May 9. J Exp Med. 2024. PMID: 38722309 Free PMC article.

Reengineering the specificity of the highly selective Clostridium botulinum protease via directed evolution.

Dyer RP, Isoda HM, Salcedo GS, Speciale G, Fletcher MH, Le LQ, Liu Y, Brami-Cherrier K, Malik SZ, Vazquez-Cintron EJ, Chu AC, Rupp DC, Jacky BPS, Nguyen TTM, Katz BB, Steward LE, Majumdar S, Brideau-Andersen AD, Weiss GA. Dyer RP, et al. Sci Rep. 2022 Jun 15;12(1):9956. doi: 10.1038/s41598-022-13617-z. Sci Rep. 2022. PMID: 35705606 Free PMC article.