Type IV transporters of pathogenic bacteria - PubMed (original) (raw)
Review
Type IV transporters of pathogenic bacteria
Drusilla L Burns. Curr Opin Microbiol. 2003 Feb.
Abstract
Type IV transporters are produced by several bacterial pathogens such as Agrobacterium tumefaciens, Bordetella pertussis, Brucella spp., Bartonella henselae, Helicobacter pylori and Legionella pneumophila. These transporters are critical for the pathogenic process in that they export important virulence factors across the membranes of the bacteria. Although the virulence factors that are exported by these transporters can be either nucleic acid or protein, the general mechanism of transport appears to be similar for members of this family. Recent findings have shed light on the architecture of type IV transporters and the roles that these transporters play in pathogenesis.
Similar articles
- Biochemistry of type IV secretion.
Burns DL. Burns DL. Curr Opin Microbiol. 1999 Feb;2(1):25-9. doi: 10.1016/s1369-5274(99)80004-6. Curr Opin Microbiol. 1999. PMID: 10047550 Review. - Bacterial type IV secretion: conjugation systems adapted to deliver effector molecules to host cells.
Christie PJ, Vogel JP. Christie PJ, et al. Trends Microbiol. 2000 Aug;8(8):354-60. doi: 10.1016/s0966-842x(00)01792-3. Trends Microbiol. 2000. PMID: 10920394 Free PMC article. Review. - Show me the substrates: modulation of host cell function by type IV secretion systems.
Nagai H, Roy CR. Nagai H, et al. Cell Microbiol. 2003 Jun;5(6):373-83. doi: 10.1046/j.1462-5822.2003.00285.x. Cell Microbiol. 2003. PMID: 12780775 Review. - Type IV secretion: intercellular transfer of macromolecules by systems ancestrally related to conjugation machines.
Christie PJ. Christie PJ. Mol Microbiol. 2001 Apr;40(2):294-305. doi: 10.1046/j.1365-2958.2001.02302.x. Mol Microbiol. 2001. PMID: 11309113 Free PMC article. Review. - Definition of a bacterial type IV secretion pathway for a DNA substrate.
Cascales E, Christie PJ. Cascales E, et al. Science. 2004 May 21;304(5674):1170-3. doi: 10.1126/science.1095211. Science. 2004. PMID: 15155952 Free PMC article.
Cited by
- Identification of a new virulence factor, BvfA, in Brucella suis.
Lavigne JP, Patey G, Sangari FJ, Bourg G, Ramuz M, O'Callaghan D, Michaux-Charachon S. Lavigne JP, et al. Infect Immun. 2005 Sep;73(9):5524-9. doi: 10.1128/IAI.73.9.5524-5529.2005. Infect Immun. 2005. PMID: 16113268 Free PMC article. - Type IV secretion: the Agrobacterium VirB/D4 and related conjugation systems.
Christie PJ. Christie PJ. Biochim Biophys Acta. 2004 Nov 11;1694(1-3):219-34. doi: 10.1016/j.bbamcr.2004.02.013. Biochim Biophys Acta. 2004. PMID: 15546668 Free PMC article. Review. - Detection of conjugation related type four secretion machinery in Aeromonas culicicola.
Rangrez AY, Dayananda KM, Atanur S, Joshi R, Patole MS, Shouche YS. Rangrez AY, et al. PLoS One. 2006 Dec 27;1(1):e115. doi: 10.1371/journal.pone.0000115. PLoS One. 2006. PMID: 17205119 Free PMC article. - Type IV secretion systems: versatility and diversity in function.
Wallden K, Rivera-Calzada A, Waksman G. Wallden K, et al. Cell Microbiol. 2010 Sep 1;12(9):1203-12. doi: 10.1111/j.1462-5822.2010.01499.x. Epub 2010 Jul 16. Cell Microbiol. 2010. PMID: 20642798 Free PMC article. Review. - A type VI secretion system of Pseudomonas aeruginosa targets a toxin to bacteria.
Hood RD, Singh P, Hsu F, Güvener T, Carl MA, Trinidad RR, Silverman JM, Ohlson BB, Hicks KG, Plemel RL, Li M, Schwarz S, Wang WY, Merz AJ, Goodlett DR, Mougous JD. Hood RD, et al. Cell Host Microbe. 2010 Jan 21;7(1):25-37. doi: 10.1016/j.chom.2009.12.007. Cell Host Microbe. 2010. PMID: 20114026 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Other Literature Sources
Miscellaneous