Kleisins: a superfamily of bacterial and eukaryotic SMC protein partners - PubMed (original) (raw)

Kleisins: a superfamily of bacterial and eukaryotic SMC protein partners

Alexander Schleiffer et al. Mol Cell. 2003 Mar.

Free article

Abstract

We describe a superfamily of eukaryotic and prokaryotic proteins (kleisins) that includes ScpA, Scc1, Rec8, and Barren. Scc1 interacts with SMC proteins through N- and C-terminal domains to form a ring-like structure. Since these are the only domains conserved among kleisins, we suggest that ring formation with SMC proteins may define this family.

PubMed Disclaimer

Similar articles

• Building and breaking bridges between sister chromatids.
  Haering CH, Nasmyth K. Haering CH, et al. Bioessays. 2003 Dec;25(12):1178-91. doi: 10.1002/bies.10361. Bioessays. 2003. PMID: 14635253 Review.
• Condensin but not cohesin SMC heterodimer induces DNA reannealing through protein-protein assembly.
  Sakai A, Hizume K, Sutani T, Takeyasu K, Yanagida M. Sakai A, et al. EMBO J. 2003 Jun 2;22(11):2764-75. doi: 10.1093/emboj/cdg247. EMBO J. 2003. PMID: 12773391 Free PMC article.
• A novel SMC protein complex in Schizosaccharomyces pombe contains the Rad18 DNA repair protein.
  Fousteri MI, Lehmann AR. Fousteri MI, et al. EMBO J. 2000 Apr 3;19(7):1691-702. doi: 10.1093/emboj/19.7.1691. EMBO J. 2000. PMID: 10747036 Free PMC article.
• Deciphering the structure of the condensin protein complex.
  Krepel D, Cheng RR, Di Pierro M, Onuchic JN. Krepel D, et al. Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):11911-11916. doi: 10.1073/pnas.1812770115. Epub 2018 Nov 1. Proc Natl Acad Sci U S A. 2018. PMID: 30385633 Free PMC article.
• Rings, bracelet or snaps: fashionable alternatives for Smc complexes.
  Huang CE, Milutinovich M, Koshland D. Huang CE, et al. Philos Trans R Soc Lond B Biol Sci. 2005 Mar 29;360(1455):537-42. doi: 10.1098/rstb.2004.1609. Philos Trans R Soc Lond B Biol Sci. 2005. PMID: 15897179 Free PMC article. Review.

Cited by

• Structural insights into the regulation of cohesion establishment by Wpl1.
  Chatterjee A, Zakian S, Hu XW, Singleton MR. Chatterjee A, et al. EMBO J. 2013 Mar 6;32(5):677-87. doi: 10.1038/emboj.2013.16. Epub 2013 Feb 8. EMBO J. 2013. PMID: 23395900 Free PMC article.
• Repurposing of synaptonemal complex proteins for kinetochores in Kinetoplastida.
  Tromer EC, Wemyss TA, Ludzia P, Waller RF, Akiyoshi B. Tromer EC, et al. Open Biol. 2021 May;11(5):210049. doi: 10.1098/rsob.210049. Epub 2021 May 19. Open Biol. 2021. PMID: 34006126 Free PMC article.
• Meiosis I chromosome segregation is established through regulation of microtubule-kinetochore interactions.
  Miller MP, Unal E, Brar GA, Amon A. Miller MP, et al. Elife. 2012 Dec 18;1:e00117. doi: 10.7554/eLife.00117. Elife. 2012. PMID: 23275833 Free PMC article.
• Reconstitution and subunit geometry of human condensin complexes.
  Onn I, Aono N, Hirano M, Hirano T. Onn I, et al. EMBO J. 2007 Feb 21;26(4):1024-34. doi: 10.1038/sj.emboj.7601562. Epub 2007 Feb 1. EMBO J. 2007. PMID: 17268547 Free PMC article.
• The diverse roles of transverse filaments of synaptonemal complexes in meiosis.
  de Boer E, Heyting C. de Boer E, et al. Chromosoma. 2006 Jun;115(3):220-34. doi: 10.1007/s00412-006-0057-5. Epub 2006 Mar 8. Chromosoma. 2006. PMID: 16523321

Publication types

MeSH terms

Substances

LinkOut - more resources

• Full Text Sources

  • Elsevier Science

• Molecular Biology Databases

  • BioCyc
  • Saccharomyces Genome Database