Epithelial polarity and tubulogenesis in vitro - PubMed (original) (raw)
Review
Epithelial polarity and tubulogenesis in vitro
Mirjam M P Zegers et al. Trends Cell Biol. 2003 Apr.
Abstract
The most fundamental type of organization of cells in metazoa is that of epithelia, which comprise sheets of adherent cells that divide the organism into topologically and physiologically distinct spaces. Some epithelial cells cover the outside of the organism; these often form multiple layers, such as in skin. Other epithelial cells form monolayers that line internal organs, and yet others form tubes that infiltrate the whole organism, carrying liquids and gases containing nutrients, waste and other materials. These tubes can form elaborate networks in the lung, kidney, reproductive passages and vasculature tree, as well as the many glands branching from the digestive system such as the liver, pancreas and salivary glands. In vitro systems can be used to study tube formation and might help to define common principles underlying the formation of diverse types of tubular organ.
Similar articles
- Apical lumen formation in renal epithelia.
Schlüter MA, Margolis B. Schlüter MA, et al. J Am Soc Nephrol. 2009 Jul;20(7):1444-52. doi: 10.1681/ASN.2008090949. Epub 2009 Jun 4. J Am Soc Nephrol. 2009. PMID: 19497970 Review. - [Personal contribution to the study of the formation of the tubular epithelial structures].
Pierreux Ch. Pierreux Ch. Bull Mem Acad R Med Belg. 2010;165(5-6):278-84. Bull Mem Acad R Med Belg. 2010. PMID: 21513114 French. - Molecular regulation of lumen morphogenesis.
Datta A, Bryant DM, Mostov KE. Datta A, et al. Curr Biol. 2011 Feb 8;21(3):R126-36. doi: 10.1016/j.cub.2010.12.003. Curr Biol. 2011. PMID: 21300279 Free PMC article. Review. - Patterning skin by planar cell polarity: the multi-talented hair designer.
Chen J, Chuong CM. Chen J, et al. Exp Dermatol. 2012 Feb;21(2):81-5. doi: 10.1111/j.1600-0625.2011.01425.x. Exp Dermatol. 2012. PMID: 22229440 Free PMC article. - Wnt to build a tube: contributions of Wnt signaling to epithelial tubulogenesis.
Miller RK, McCrea PD. Miller RK, et al. Dev Dyn. 2010 Jan;239(1):77-93. doi: 10.1002/dvdy.22059. Dev Dyn. 2010. PMID: 19681164 Free PMC article. Review.
Cited by
- Annexin A1 is a polarity cue that directs mitotic spindle orientation during mammalian epithelial morphogenesis.
Fankhaenel M, Hashemi FSG, Mourao L, Lucas E, Hosawi MM, Skipp P, Morin X, Scheele CLGJ, Elias S. Fankhaenel M, et al. Nat Commun. 2023 Jan 11;14(1):151. doi: 10.1038/s41467-023-35881-x. Nat Commun. 2023. PMID: 36631478 Free PMC article. - Rho activation drives luminal collapse and eversion in epithelial acini.
Narayanan V, Purkayastha P, Yu B, Pendyala K, Chukkapalli S, Cabe JI, Dickinson RB, Conway DE, Lele TP. Narayanan V, et al. Biophys J. 2023 Sep 19;122(18):3630-3645. doi: 10.1016/j.bpj.2023.01.005. Epub 2023 Jan 7. Biophys J. 2023. PMID: 36617192 Free PMC article. - Role of extracellular matrix components and structure in new renal models in vitro.
Lacueva-Aparicio A, Lindoso RS, Mihăilă SM, Giménez I. Lacueva-Aparicio A, et al. Front Physiol. 2022 Dec 7;13:1048738. doi: 10.3389/fphys.2022.1048738. eCollection 2022. Front Physiol. 2022. PMID: 36569770 Free PMC article. Review. - Luminal and Glandular Epithelial Cells from the Porcine Endometrium maintain Cell Type-Specific Marker Gene Expression in Air-Liquid Interface Culture.
Schmidhauser M, Ulbrich SE, Schoen J. Schmidhauser M, et al. Stem Cell Rev Rep. 2022 Dec;18(8):2928-2938. doi: 10.1007/s12015-022-10410-3. Epub 2022 Jul 18. Stem Cell Rev Rep. 2022. PMID: 35849251 Free PMC article. - Membrane Lipids in Epithelial Polarity: Sorting out the PIPs.
Bugda Gwilt K, Thiagarajah JR. Bugda Gwilt K, et al. Front Cell Dev Biol. 2022 May 31;10:893960. doi: 10.3389/fcell.2022.893960. eCollection 2022. Front Cell Dev Biol. 2022. PMID: 35712665 Free PMC article. Review.