Transient relief of asthma symptoms during jaundice: a possible beneficial role of bilirubin - PubMed (original) (raw)
Case Reports
doi: 10.1620/tjem.199.193.
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- PMID: 12703664
- DOI: 10.1620/tjem.199.193
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Case Reports
Transient relief of asthma symptoms during jaundice: a possible beneficial role of bilirubin
Takashi Ohrui et al. Tohoku J Exp Med. 2003 Mar.
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Abstract
Bilirubin arises from enzymatic reduction by biliverdin reductase of biliverdin, a product of heme oxygenase activity. Recent literature describes that bilirubin is a major physiologic antioxidant that can protect cells from chemical oxidants such as hydrogen peroxide. Recently, it has been reported that oxidative stress may play a crucial role in the pathogenesis of asthma. We report a case of complete resolution of persistent difficult-to-control asthma in accordance with increased levels of serum bilirubin due to acute hepatitis B. The present case suggests that anti-oxidative agents might be effective for the treatment of asthma.
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