Phagocyte sabotage: disruption of macrophage signalling by bacterial pathogens - PubMed (original) (raw)

Review

doi: 10.1038/nrm1104.

Affiliations

Review

Phagocyte sabotage: disruption of macrophage signalling by bacterial pathogens

Carrie M Rosenberger et al. Nat Rev Mol Cell Biol. 2003 May.

Abstract

Macrophages function at the front line of immune defences against incoming pathogens. But the ability of macrophages to internalize bacteria, migrate, recruit other immune cells to the site of infection and influence the nature of the immune response can provide unintended benefits for bacterial pathogens that are able to subvert or co-opt these normally effective defences. This review highlights recent advances in our understanding of the many interference strategies that are used by bacterial pathogens to undermine macrophage signalling.

PubMed Disclaimer

Similar articles

Cited by

Publication types

MeSH terms

Substances

LinkOut - more resources