Influences of probiotic bacteria on organic acid production by pig caecal bacteria in vitro - PubMed (original) (raw)
Review
Influences of probiotic bacteria on organic acid production by pig caecal bacteria in vitro
Takashi Sakata et al. Proc Nutr Soc. 2003 Feb.
Abstract
The mechanism of action of probiotics is largely unknown. A potential mechanism should be to increase the production of short-chain fatty acids (SCFA), known modulators of gut functions, by the bacterial ecosystem in the large intestine. The present paper reviews our recent studies in which the capacity of probiotic bacteria to increase the production of SCFA by pig caecal bacteria was investigated using batch-culture and continuous-culture techniques. All four commercial probiotic preparations and three strains of probiotic bacteria dose-dependently accelerated the net production of SCFA, succinic acid and lactic acid without changing the acid profile, and slowed the net production of NH4. Effects on organic acid production did not vary among different probiotic species. Neither probiotic preparations nor probiotic bacteria affected the organic acid production from glucose, gastric mucin, starch or lactose, or organic acids produced:added saccharide. Glucose abolished these effects of probiotic preparations. However, the capacity of probiotics to increase SCFA production was not modified by gastric mucin, starch or lactose. These results indicate that probiotic bacteria increase SCFA production by accelerating the breakdown of carbohydrates that are resistant to indigenous bacteria, and suggest that the concept of prebiotics in terms of SCFA production as a measure of probiotic function is arguable.
Similar articles
- Probiotic preparations dose-dependently increase net production rates of organic acids and decrease that of ammonia by pig cecal bacteria in batch culture.
Sakata T, Kojima T, Fujieda M, Miyakozawa M, Takahashi M, Ushida K. Sakata T, et al. Dig Dis Sci. 1999 Jul;44(7):1485-93. doi: 10.1023/a:1026624423767. Dig Dis Sci. 1999. PMID: 10489936 - Commercial probiotic bacteria and prebiotic carbohydrates: a fundamental study on prebiotics uptake, antimicrobials production and inhibition of pathogens.
Cruz-Guerrero A, Hernández-Sánchez H, Rodríguez-Serrano G, Gómez-Ruiz L, García-Garibay M, Figueroa-González I. Cruz-Guerrero A, et al. J Sci Food Agric. 2014 Aug;94(11):2246-52. doi: 10.1002/jsfa.6549. Epub 2014 Jan 31. J Sci Food Agric. 2014. PMID: 24374769 - Regulation of short-chain fatty acid production.
Macfarlane S, Macfarlane GT. Macfarlane S, et al. Proc Nutr Soc. 2003 Feb;62(1):67-72. doi: 10.1079/PNS2002207. Proc Nutr Soc. 2003. PMID: 12740060 Review. - Probiotics.
Gupta V, Garg R. Gupta V, et al. Indian J Med Microbiol. 2009 Jul-Sep;27(3):202-9. doi: 10.4103/0255-0857.53201. Indian J Med Microbiol. 2009. PMID: 19584499 Review.
Cited by
- Duodenal and faecal microbiota of celiac children: molecular, phenotype and metabolome characterization.
Di Cagno R, De Angelis M, De Pasquale I, Ndagijimana M, Vernocchi P, Ricciuti P, Gagliardi F, Laghi L, Crecchio C, Guerzoni ME, Gobbetti M, Francavilla R. Di Cagno R, et al. BMC Microbiol. 2011 Oct 4;11:219. doi: 10.1186/1471-2180-11-219. BMC Microbiol. 2011. PMID: 21970810 Free PMC article. - Discovering probiotic microorganisms: in vitro, in vivo, genetic and omics approaches.
Papadimitriou K, Zoumpopoulou G, Foligné B, Alexandraki V, Kazou M, Pot B, Tsakalidou E. Papadimitriou K, et al. Front Microbiol. 2015 Feb 17;6:58. doi: 10.3389/fmicb.2015.00058. eCollection 2015. Front Microbiol. 2015. PMID: 25741323 Free PMC article. Review. - The Networked Interaction between Probiotics and Intestine in Health and Disease: A Promising Success Story.
Skoufou M, Tsigalou C, Vradelis S, Bezirtzoglou E. Skoufou M, et al. Microorganisms. 2024 Jan 18;12(1):194. doi: 10.3390/microorganisms12010194. Microorganisms. 2024. PMID: 38258020 Free PMC article. Review. - Dietary supplementation with fiber, "biotics," and spray-dried plasma affects apparent total tract macronutrient digestibility and the fecal characteristics, fecal microbiota, and immune function of adult dogs.
Lee AH, Lin CY, Do S, Oba PM, Belchik SE, Steelman AJ, Schauwecker A, Swanson KS. Lee AH, et al. J Anim Sci. 2022 Mar 1;100(3):skac048. doi: 10.1093/jas/skac048. J Anim Sci. 2022. PMID: 35180312 Free PMC article. - Selective Manipulation of the Gut Microbiota Improves Immune Status in Vertebrates.
Montalban-Arques A, De Schryver P, Bossier P, Gorkiewicz G, Mulero V, Gatlin DM 3rd, Galindo-Villegas J. Montalban-Arques A, et al. Front Immunol. 2015 Oct 9;6:512. doi: 10.3389/fimmu.2015.00512. eCollection 2015. Front Immunol. 2015. PMID: 26500650 Free PMC article. Review.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources