New roles for connexons - PubMed (original) (raw)

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New roles for connexons

Lisa Ebihara. News Physiol Sci. 2003 Jun.

Abstract

Connexons or gap junction hemichannels are large, nonselective ion channels that reside in the nonjunctional plasma membrane before their assembly into gap junction channels. Increasing evidence suggests that these channels can open under certain conditions and may participate in a number of cellular processes, including the release of small metabolites such as ATP and NAD(+), which are involved in paracrine signaling.

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