Functional-anatomic correlates of control processes in memory - PubMed (original) (raw)

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Functional-anatomic correlates of control processes in memory

Randy L Buckner. J Neurosci. 2003.

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Figures

Figure 1.

Figure 1.

Frontal regions activated during memory retrieval show a roughly posterior to anterior gradient of functional specialization. Posterior regions (red) tend to modulate on the basis of retrieved content, and more anterior regions (blue) modulate based on the level and type of controlled processing demand. Frontal-polar regions(green) exhibit complex properties that are content independent and associated with high-level task goals (see text).

Figure 2.

Figure 2.

During retrieval of specific episodes, frontal-polar regions demonstrate prolonged signal change, suggesting a contribution to temporally extended processes that establish a task set or retrieval mode. A, The time course of posterior and anterior frontal regions is shown from a functional magnetic resonance imaging study of memory retrieval. Note that the timescale(in seconds) reflects the temporal blurring of the hemodynamic response (Logethetis, 2003). Adapted from Schacter et al.(1997).B, The time course of evoked response potentials measured over anterior frontal scalp sites. A slowly evolving change in the waveform is noted during the periods of remembering that extends across individual items. Adapted from Düzel et al. (1999).

Figure 3.

Figure 3.

Under-recruitment and nonselective recruitment of frontal regions in older adults are illustrated. A, Anterior left frontal regions are under-recruited in older adults as compared with younger adults during intentional memorization. B, Older adults, paradoxically, show increased activation in regions not typically associated with processing in younger adults (nonselective recruitment). In this example, young adults show selective recruitment of left posterior frontal regions during word encoding. Older adults show greater relative activation of the homologous right frontal region. Adapted from Logan et al (2002). See Cabeza (2002) and Reuter-Lorenz (2002) for additional examples.

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