Rocks: multifunctional kinases in cell behaviour - PubMed (original) (raw)

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doi: 10.1038/nrm1128.

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• PMID: 12778124
• DOI: 10.1038/nrm1128

Review

Rocks: multifunctional kinases in cell behaviour

Kirsi Riento et al. Nat Rev Mol Cell Biol. 2003 Jun.

Abstract

ROCKs, or Rho kinases, are serine/threonine kinases that are involved in many aspects of cell motility, from smooth-muscle contraction to cell migration and neurite outgrowth. Recent experiments have defined new functions of ROCKs in cells, including centrosome positioning and cell-size regulation, which might contribute to various physiological and pathological states.

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