Severe acute respiratory syndrome: temporal stability and geographic variation in case-fatality rates and doubling times - PubMed (original) (raw)

Severe acute respiratory syndrome: temporal stability and geographic variation in case-fatality rates and doubling times

Alison P Galvani et al. Emerg Infect Dis. 2003 Aug.

Abstract

We analyzed temporal stability and geographic trends in cumulative case-fatality rates and average doubling times of severe acute respiratory syndrome (SARS). In part, we account for correlations between case-fatality rates and doubling times through differences in control measures. Factors that may alter future estimates of case-fatality rates, reasons for heterogeneity in doubling times among countries, and implications for the control of SARS are discussed.

PubMed Disclaimer

Figures

Figure 1

Figure 1

Cumulative case-fatality rates for severe acute respiratory syndrome over time.

Figure 2

Figure 2

Cumulative case-fatality rate for severe acute respiratory syndrome compared with average doubling time as of May 12, 2003.

Figure 3

Figure 3

Time series of log of average doubling time for severe acute respiratory syndrome.

Figure 4

Figure 4

Observed and expected cumulative number of cases of severe acute respiratory syndrome in China.

References

    1. Cumulative number of reported cases of severe acute respiratory syndrome (SARS). Geneva: World Health Organization, 2003. Cited May 12, 2003. Available from: URL: http://www.who.int/csr/sarscountry/en/
    1. Donnelly CA, Ghani AC, Leung GM, Hedley AJ, Fraser C, Riley S, et al. Epidemiological determinants of spread of causal agent of severe acute respiratory syndrome in Hong Kong. Lancet online May 7, 2003. Available from: URL: http://image.thelancet.com/extras/03art4453web.pdf -PMC -PubMed
    1. Cleveland WS. Robust locally weighted regression and smoothing scatterplots. J Am Stat Assoc. 1979;74:829–36. 10.2307/2286407 -DOI
    1. Poutanen SM, Low DE, Henry B, Finkelstein S, Rose D, Green K, et al. Identification of severe acute respiratory syndrome in Canada. N Engl J Med. 2003;348:1995–2005. 10.1056/NEJMoa030634 -DOI -PubMed
    1. Koh WP, Taylor MB, Hughes K, Chew SK, Fong CW, Phoon MC, et al. Seroprevalence of IgG antibodies against Chlamydia pneumoniae in Chinese, Malays and Asian Indians in Singapore. Int J Epidemiol. 2002;31:1001–7. 10.1093/ije/31.5.1001 -DOI -PubMed

Publication types

MeSH terms

LinkOut - more resources