Inositol hexakisphosphate receptor identified as the clathrin assembly protein AP-2 - PubMed (original) (raw)
Comparative Study
. 1992 Aug 31;187(1):158-63.
doi: 10.1016/s0006-291x(05)81473-1.
Affiliations
- PMID: 1325787
- DOI: 10.1016/s0006-291x(05)81473-1
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Comparative Study
Inositol hexakisphosphate receptor identified as the clathrin assembly protein AP-2
S M Voglmaier et al. Biochem Biophys Res Commun. 1992.
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Abstract
To clarify the function of the receptor binding protein for inositol hexakisphosphate (IP6), we obtained a partial amino acid sequence from the purified protein and a partial nucleotide sequence from a cDNA clone of the gene. The sequences are essentially identical to those of the alpha-subunit of the clathrin assembly protein AP-2. The IP6 receptor protein analyzed by SDS-PAGE contains a series of subunits which are the same as those of AP-2. Antibodies to AP-2 react with the IP6 receptor protein in immunoblot analysis.
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