A genetic map of the mouse suitable for typing intraspecific crosses - PubMed (original) (raw)

A genetic map of the mouse suitable for typing intraspecific crosses

W Dietrich et al. Genetics. 1992 Jun.

Abstract

We report the construction of a genetic linkage map of the mouse, consisting entirely of genetic markers that can be rapidly typed by polymerase chain reaction and that show a high degree of polymorphism among inbred laboratory strains. Specifically, the map contains 317 simple sequence length polymorphisms at an average spacing of 4.3 cM and is detectably linked to approximately 99% of the mouse genome. In typical crosses between inbred laboratory strains, about 50% of the markers are polymorphic, making it straightforward to follow inheritance in almost any cross.

PubMed Disclaimer

References

    1. Nucleic Acids Res. 1990 Jul 25;18(14):4123-30 - PubMed
    1. Mol Cell Biol. 1990 Aug;10(8):4294-302 - PubMed
    1. Genetics. 1989 May;122(1):153-61 - PubMed
    1. Genetics. 1989 Sep;123(1):165-72 - PubMed
    1. Genomics. 1989 Nov;5(4):699-709 - PubMed

Publication types

MeSH terms

Substances

LinkOut - more resources