T cells and eosinophils in the pathogenesis of asthma - PubMed (original) (raw)

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T cells and eosinophils in the pathogenesis of asthma

C J Corrigan et al. Immunol Today. 1992 Dec.

Abstract

Persistent asthma is characterized by chronic inflammation of the bronchial mucosa, where T cells and eosinophils are prominent. This article summarizes the evidence that asthmatic bronchial inflammation is initiated and propagated by cytokines secreted by activated T cells and other cells, and describes how the release of specific cytokines could result in local preferential accumulation and activation of eosinophils.

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