Sustained and transient calcium currents in horizontal cells of the white bass retina - PubMed (original) (raw)
Sustained and transient calcium currents in horizontal cells of the white bass retina
J M Sullivan et al. J Gen Physiol. 1992 Jan.
Abstract
Calcium currents were recorded from cultured horizontal cells (HCs) isolated from adult white bass retinas, using the whole-cell patch-clamp technique. Ca2+ currents were enhanced using 10 mM extracellular Ca2+, while Na+ and K+ currents were pharmacologically suppressed. Two components of the Ca2+ current, one transient, the other sustained, were found. The large transient component of the Ca2+ current, which has not been seen before in HCs, is similar, but not identical, to the T-type Ca2+ current described previously in a variety of preparations. The sustained component of the Ca2+ current is similar, but not identical, to the L-type current described in other preparations. FTX, a factor isolated from the venom of the funnel-web spider, Agelenopsis aperta, preferentially and irreversibly blocks the sustained component of the Ca2+ current at very dilute concentrations. The sustained component of the Ca2+ current inactivates slowly, over the course of 15-60 s, in some HCs. This inactivation of the sustained Ca2+ current, when present, is primarily voltage dependent rather than Ca2+ dependent.
Similar articles
- Low- and high-voltage-activated calcium currents in rat spinal dorsal horn neurons.
Ryu PD, Randic M. Ryu PD, et al. J Neurophysiol. 1990 Feb;63(2):273-85. doi: 10.1152/jn.1990.63.2.273. J Neurophysiol. 1990. PMID: 1690273 - Adenosine modulation of calcium currents in postganglionic neurones of avian cultured ciliary ganglia.
Bennett MR, Kerr R, Khurana G. Bennett MR, et al. Br J Pharmacol. 1992 May;106(1):25-32. doi: 10.1111/j.1476-5381.1992.tb14287.x. Br J Pharmacol. 1992. PMID: 1380383 Free PMC article. - Characterization of K+ and Ca2+ ionic currents in glomerulosa cells from human adrenal glands.
Payet MD, Durroux T, Bilodeau L, Guillon G, Gallo-Payet N. Payet MD, et al. Endocrinology. 1994 Jun;134(6):2589-98. doi: 10.1210/endo.134.6.7515004. Endocrinology. 1994. PMID: 7515004 - Two types of pharmacologically distinct Ca(2+) currents with voltage-dependent similarities in zona fasciculata cells isolated from bovine adrenal gland.
Guyot A, Dupré-Aucouturier S, Ojeda C, Rougier O, Bilbaut A. Guyot A, et al. J Membr Biol. 2000 Jan 15;173(2):149-63. doi: 10.1007/s002320001016. J Membr Biol. 2000. PMID: 10630930 - Permeation and gating properties of the L-type calcium channel in mouse pancreatic beta cells.
Smith PA, Aschroft FM, Fewtrell CM. Smith PA, et al. J Gen Physiol. 1993 May;101(5):767-97. doi: 10.1085/jgp.101.5.767. J Gen Physiol. 1993. PMID: 7687645 Free PMC article.
Cited by
- A multiscale continuum model of the vertebrate outer retina: The temporal dynamics of background-induced flicker enhancement.
Baer SM, Chang S, Crook SM, Gardner CL, Jones JR, Ringhofer C, Nelson RF. Baer SM, et al. J Theor Biol. 2021 Sep 21;525:110763. doi: 10.1016/j.jtbi.2021.110763. Epub 2021 May 15. J Theor Biol. 2021. PMID: 34000285 Free PMC article. - Spontaneous action potentials in retinal horizontal cells of goldfish (Carassius auratus) are dependent upon L-type Ca2+ channels and ryanodine receptors.
Country MW, Campbell BFN, Jonz MG. Country MW, et al. J Neurophysiol. 2019 Dec 1;122(6):2284-2293. doi: 10.1152/jn.00240.2019. Epub 2019 Oct 9. J Neurophysiol. 2019. PMID: 31596629 Free PMC article. - Voltage- and calcium-gated ion channels of neurons in the vertebrate retina.
Van Hook MJ, Nawy S, Thoreson WB. Van Hook MJ, et al. Prog Retin Eye Res. 2019 Sep;72:100760. doi: 10.1016/j.preteyeres.2019.05.001. Epub 2019 May 10. Prog Retin Eye Res. 2019. PMID: 31078724 Free PMC article. Review. - Calcium dynamics and regulation in horizontal cells of the vertebrate retina: lessons from teleosts.
Country MW, Jonz MG. Country MW, et al. J Neurophysiol. 2017 Feb 1;117(2):523-536. doi: 10.1152/jn.00585.2016. Epub 2016 Nov 2. J Neurophysiol. 2017. PMID: 27832601 Free PMC article. Review. - Calcium channels in rat horizontal cells regulate feedback inhibition of photoreceptors through an unconventional GABA- and pH-sensitive mechanism.
Liu X, Hirano AA, Sun X, Brecha NC, Barnes S. Liu X, et al. J Physiol. 2013 Jul 1;591(13):3309-24. doi: 10.1113/jphysiol.2012.248179. Epub 2013 Apr 22. J Physiol. 2013. PMID: 23613534 Free PMC article.
References
- Vision Res. 1985;25(9):1187-93 - PubMed
- J Neurophysiol. 1988 Oct;60(4):1322-32 - PubMed
- Vision Res. 1972 Apr;12(4):573-88 - PubMed
- J Physiol. 1971 Apr;214(2):265-94 - PubMed
- J Neurophysiol. 1981 Jan;45(1):86-97 - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Miscellaneous