Endothelial cell interactions with granulocytes: tethering and signaling molecules - PubMed (original) (raw)

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Endothelial cell interactions with granulocytes: tethering and signaling molecules

G A Zimmerman et al. Immunol Today. 1992 Mar.

Abstract

The adhesion of granulocytes to endothelial cells requires regulated expression of molecules on both the endothelial cell and the granulocyte. These pro-adhesive molecules have diverse structures and mechanisms of expression, and act either to tether the two cells together or as signals that induce activation-dependent adhesion events. Combinations of tethering and signaling molecules regulate endothelial-cell-granulocyte interactions at the endothelial surface.

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