Effects of chronia excess salt ingestion. Evidence that genetic factors play an important role in susceptibility to experimental hypertension - PubMed (original) (raw)
Effects of chronia excess salt ingestion. Evidence that genetic factors play an important role in susceptibility to experimental hypertension
L K DAHL et al. J Exp Med. 1962.
Abstract
Using the genetic technique of selective inbreeding, it has been possible to quickly develop two statistically separable populations from one unselected strain of Sprague-Dawley rats. One of these is very sensitive, the other very resistant, to the development of experimental hypertension from a high salt diet. It was suggested that similar genetic factors operate in man.
Comment in
- Lewis Dahl and the genetics of salt-induced hypertension.
Bashyam H. Bashyam H. J Exp Med. 2007 Jul 9;204(7):1507. doi: 10.1084/jem.2047fta. J Exp Med. 2007. PMID: 17650543 Free PMC article.
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