Barrett's esophagus: age, prevalence, and extent of columnar epithelium - PubMed (original) (raw)
Barrett's esophagus: age, prevalence, and extent of columnar epithelium
A J Cameron et al. Gastroenterology. 1992 Oct.
Abstract
The development of Barrett's esophagus was studied using data from 51,311 patients undergoing upper gastrointestinal endoscopy between 1976 and 1989. Three hundred seventy-seven patients had greater than or equal to 3-cm columnar epithelium in the esophagus and no carcinoma. The prevalence of Barrett's esophagus increased with age to reach a plateau by the seventh decade. Half of the maximum prevalence was reached by age 40 years, the estimated median age of development of the disorder. Unlike prevalence, the mean length of columnar epithelium did not increase with age. No significant change in length was found in 21 patients followed up for a mean of 7.3 years (mean initial length, 8.29 +/- 0.85 cm; mean final length, 8.33 +/- 0.77 cm). The length of columnar epithelium did not increase in the presence of esophagitis or decrease when esophagitis was absent. Mean age at diagnosis of Barrett's esophagus was 63 years without carcinoma and 64 years in a separate group of patients with adenocarcinoma. The data are consistent with a fairly rapid evolution of Barrett's esophagus to its full length with little subsequent change. Barrett's esophagus may develop more than 20 years before the mean age of clinical recognition or the development of esophageal adenocarcinoma.
Comment in
- Molecular events in Barrett's metaplasia.
Jankowski J. Jankowski J. Gastroenterology. 1993 Apr;104(4):1235-6. doi: 10.1016/0016-5085(93)90311-y. Gastroenterology. 1993. PMID: 8318112 No abstract available. - Evolution of Barrett's esophagus: the jury is still out.
Afridi SA, Shaw-Stiffel TA. Afridi SA, et al. Gastroenterology. 1993 Apr;104(4):1236. doi: 10.1016/0016-5085(93)90313-2. Gastroenterology. 1993. PMID: 8462816 No abstract available.
Similar articles
- Short segment Barrett's esophagus: relationship of age with extent of intestinal metaplasia.
Benipal P, Garewal HS, Sampliner RE, Martinez P, Hayden CW, Fass R. Benipal P, et al. Am J Gastroenterol. 2001 Nov;96(11):3084-8. doi: 10.1111/j.1572-0241.2001.05262.x. Am J Gastroenterol. 2001. PMID: 11721753 - LOW PREVALENCE OF BARRETT'S ESOPHAGUS IN A RISK AREA FOR ESOPHAGEAL CANCER IN SOUTH OF BRAZIL.
DE Carli DM, Araujo AF, Fagundes RB. DE Carli DM, et al. Arq Gastroenterol. 2017 Dec;54(4):305-307. doi: 10.1590/S0004-2803.201700000-45. Epub 2017 Sep 21. Arq Gastroenterol. 2017. PMID: 28954045 - Dysplasia in short-segment Barrett's esophagus: a prospective 3-year follow-up.
Sharma P, Morales TG, Bhattacharyya A, Garewal HS, Sampliner RE. Sharma P, et al. Am J Gastroenterol. 1997 Nov;92(11):2012-6. Am J Gastroenterol. 1997. PMID: 9362182 - [Epidemiology of Barrett's esophagus--comparison of Japan and the West].
Hanai M, Kusano M, Kawamura O, Shimoyama Y, Maeda M. Hanai M, et al. Nihon Rinsho. 2005 Aug;63(8):1333-9. Nihon Rinsho. 2005. PMID: 16101218 Review. Japanese. - [Endoscopic diagnosis of Barrett's esophagus].
Hoshihara Y, Kogure T, Yamamoto T, Hashimoto M, Hoteya O. Hoshihara Y, et al. Nihon Rinsho. 2005 Aug;63(8):1394-8. Nihon Rinsho. 2005. PMID: 16101228 Review. Japanese.
Cited by
- Biomarkers in the molecular pathogenesis of esophageal (Barrett) adenocarcinoma.
Williams LJ, Guernsey DL, Casson AG. Williams LJ, et al. Curr Oncol. 2006 Feb;13(1):33-43. doi: 10.3747/co.v13i1.76. Curr Oncol. 2006. PMID: 17576439 Free PMC article. - [Barrett esophagus: epidemiology, incidence of carcinoma, need for screening].
Arnold R, Wied M. Arnold R, et al. Internist (Berl). 2003 Jan;44(1):43-4, 47-51. doi: 10.1007/s00108-002-0813-4. Internist (Berl). 2003. PMID: 12677704 German. No abstract available. - Gastroesophageal reflux disease: relationship between clinical and histological features. GOSPE. Gruppo Operativo per lo Studio delle Precancerosi dell'Esofago.
Aste H, Bonelli L, Ferraris R, Conio M, Lapertosa G. Aste H, et al. Dig Dis Sci. 1999 Dec;44(12):2412-8. doi: 10.1023/a:1026666417658. Dig Dis Sci. 1999. PMID: 10630490 - Barrett's oesophagus and adenocarcinoma.
Caygill CP, Watson A, Lao-Sirieix P, Fitzgerald RC. Caygill CP, et al. World J Surg Oncol. 2004 May 7;2:12. doi: 10.1186/1477-7819-2-12. World J Surg Oncol. 2004. PMID: 15132744 Free PMC article. No abstract available. - Epidemiology and natural history of intestinal metaplasia of the gastroesophageal junction and Barrett's esophagus: a population-based study.
Jung KW, Talley NJ, Romero Y, Katzka DA, Schleck CD, Zinsmeister AR, Dunagan KT, Lutzke LS, Wu TT, Wang KK, Frederickson M, Geno DM, Locke GR, Prasad GA. Jung KW, et al. Am J Gastroenterol. 2011 Aug;106(8):1447-55; quiz 1456. doi: 10.1038/ajg.2011.130. Epub 2011 Apr 12. Am J Gastroenterol. 2011. PMID: 21483461 Free PMC article.
MeSH terms
LinkOut - more resources
Full Text Sources
Other Literature Sources