Localization of a DNA replication origin and termination zone on chromosome III of Saccharomyces cerevisiae - PubMed (original) (raw)
Localization of a DNA replication origin and termination zone on chromosome III of Saccharomyces cerevisiae
J Zhu et al. Mol Cell Biol. 1992 Oct.
Abstract
Two-dimensional gel electrophoretic replicon mapping techniques were used to identify all functional DNA replication origins and termini in a 26.5-kbp stretch in the left arm of yeast chromosome III. Only one origin was detected; it coincided with an ARS element (ARS306), as have all previously mapped yeast origins. A replication termination region was identified in a 4.3-kbp stretch at the telomere-proximal end of the investigated region, between the origin identified in this paper and the neighboring, previously mapped, ARS305-associated origin (previously called the A6C origin). Termination does not occur at a specific site; instead, it appears to be the consequence of replication forks converging in a stretch of DNA of at least 4.3 kbp.
References
- Nucleic Acids Res. 1990 Feb 11;18(3):647-52 - PubMed
- Mol Cell Biol. 1991 Mar;11(3):1464-72 - PubMed
- Annu Rev Genet. 1975;9:245-84 - PubMed
- Nucleic Acids Res. 1992 Apr 11;20(7):1463-9 - PubMed
- Annu Rev Cell Biol. 1991;7:375-402 - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Molecular Biology Databases