Cognitive control mechanisms revealed by ERP and fMRI: evidence from repeated task-switching - PubMed (original) (raw)

Comparative Study

. 2003 Aug 15;15(6):785-99.

doi: 10.1162/089892903322370717.

Affiliations

• PMID: 14511532
• DOI: 10.1162/089892903322370717

Free article

Comparative Study

Cognitive control mechanisms revealed by ERP and fMRI: evidence from repeated task-switching

R Swainson et al. J Cogn Neurosci. 2003.

Free article

Abstract

We investigated the extent to which a common neural mechanism is involved in task set-switching and response withholding, factors that are frequently confounded in task-switching and go/no-go paradigms. Subjects' brain activity was measured using event-related electrical potentials (ERPs) and event-related functional MRI (fMRI) neuroimaging in separate studies using the same cognitive paradigm. Subjects made compatible left/right keypress responses to left/right arrow stimuli of 1000 msec duration; they switched every two trials between responding at stimulus onset (GO task-green arrows) and stimulus offset (WAIT task-red arrows). With-holding an immediate response (WAIT vs. GO) elicited an enhancement of the frontal N2 ERP and lateral PFC activation of the right hemisphere, both previously associated with the "no-go" response, but only on switch trials. Task-switching (switch vs. nonswitch) was associated with frontal N2 amplification and right hemisphere ventrolateral PFC activation, but only for the WAIT task. The anterior cingulate cortex (ACC) was the only brain region to be activated for both types of task switch, but this activation was located more rostrally for the WAIT than for the GO switch trials. We conclude that the frontal N2 ERP and lateral PFC activation are not markers for withholding an immediate response or switching tasks per se, but are associated with switching into a response-suppression mode. Different regions within the ACC may be involved in two processes integral to task-switching: processing response conflict (rostral ACC) and overcoming prior response suppression (caudal ACC).

PubMed Disclaimer

Similar articles

• Who comes first? The role of the prefrontal and parietal cortex in cognitive control.
  Brass M, Ullsperger M, Knoesche TR, von Cramon DY, Phillips NA. Brass M, et al. J Cogn Neurosci. 2005 Sep;17(9):1367-75. doi: 10.1162/0898929054985400. J Cogn Neurosci. 2005. PMID: 16197690
• Attentional control of task and response in lateral and medial frontal cortex: brain activity and reaction time distributions.
  Aarts E, Roelofs A, van Turennout M. Aarts E, et al. Neuropsychologia. 2009 Aug;47(10):2089-99. doi: 10.1016/j.neuropsychologia.2009.03.019. Epub 2009 Apr 5. Neuropsychologia. 2009. PMID: 19467359
• Do women with fragile X syndrome have problems in switching attention: preliminary findings from ERP and fMRI.
  Cornish K, Swainson R, Cunnington R, Wilding J, Morris P, Jackson G. Cornish K, et al. Brain Cogn. 2004 Apr;54(3):235-9. doi: 10.1016/j.bandc.2004.02.017. Brain Cogn. 2004. PMID: 15050782
• Have we been asking the right questions when assessing response inhibition in go/no-go tasks with fMRI? A meta-analysis and critical review.
  Criaud M, Boulinguez P. Criaud M, et al. Neurosci Biobehav Rev. 2013 Jan;37(1):11-23. doi: 10.1016/j.neubiorev.2012.11.003. Epub 2012 Nov 16. Neurosci Biobehav Rev. 2013. PMID: 23164813 Review.
• Event-related potentials and functional MRI: a comparison of localization in sensory, perceptual and cognitive tasks.
  McCarthy G. McCarthy G. Electroencephalogr Clin Neurophysiol Suppl. 1999;49:3-12. Electroencephalogr Clin Neurophysiol Suppl. 1999. PMID: 10533078 Review.

Cited by

• ERP correlates of response inhibition after-effects in the stop signal task.
  Upton DJ, Enticott PG, Croft RJ, Cooper NR, Fitzgerald PB. Upton DJ, et al. Exp Brain Res. 2010 Oct;206(4):351-8. doi: 10.1007/s00221-010-2369-1. Epub 2010 Sep 28. Exp Brain Res. 2010. PMID: 20878149
• Converging evidence for a fronto-basal-ganglia network for inhibitory control of action and cognition.
  Aron AR, Durston S, Eagle DM, Logan GD, Stinear CM, Stuphorn V. Aron AR, et al. J Neurosci. 2007 Oct 31;27(44):11860-4. doi: 10.1523/JNEUROSCI.3644-07.2007. J Neurosci. 2007. PMID: 17978025 Free PMC article. Review. No abstract available.
• The development of anticipatory cognitive control processes in task-switching: an ERP study in children, adolescents, and young adults.
  Manzi A, Nessler D, Czernochowski D, Friedman D. Manzi A, et al. Psychophysiology. 2011 Sep;48(9):1258-75. doi: 10.1111/j.1469-8986.2011.01192.x. Epub 2011 Mar 3. Psychophysiology. 2011. PMID: 21371043 Free PMC article.
• Randomised prior feedback modulates neural signals of outcome monitoring.
  Mushtaq F, Wilkie RM, Mon-Williams MA, Schaefer A. Mushtaq F, et al. Neuroimage. 2016 Jan 15;125:868-879. doi: 10.1016/j.neuroimage.2015.10.046. Epub 2015 Oct 20. Neuroimage. 2016. PMID: 26497268 Free PMC article. Clinical Trial.
• The Complex Pre-Execution Stage of Auditory Cognitive Control: ERPs Evidence from Stroop Tasks.
  Yu B, Wang X, Ma L, Li L, Li H. Yu B, et al. PLoS One. 2015 Sep 14;10(9):e0137649. doi: 10.1371/journal.pone.0137649. eCollection 2015. PLoS One. 2015. PMID: 26368570 Free PMC article.

Publication types

MeSH terms

LinkOut - more resources

• Full Text Sources

  • CORE
  • Silverchair Information Systems

• Other Literature Sources

  • The Lens - Patent Citations Database

• Medical

  • MedlinePlus Health Information

• Miscellaneous

  • NCI CPTAC Assay Portal