Molecular dimensions of gastrointestinal tumors: some thoughts for digestion - PubMed (original) (raw)
Review
. 2003 Nov 1;122A(4):303-14.
doi: 10.1002/ajmg.a.20473.
Affiliations
- PMID: 14518068
- DOI: 10.1002/ajmg.a.20473
Review
Molecular dimensions of gastrointestinal tumors: some thoughts for digestion
M Michael Cohen Jr. Am J Med Genet A. 2003.
Abstract
Topics discussed here include PTEN mutations and colonic polyps; WNT signaling, APC, beta-catenin, and gastrointestinal neoplasms; mismatch-repair genes (MLH1, MSH2, PMS1, MSH6) and hereditary nonpolyposis colorectal cancer; MYH mutations and autosomal recessive colorectal tumors; STK11 mutations and Peutz-Jeghers syndrome; TGFbeta and gastrointestinal cancer; BMPR1A mutations and juvenile polyposis; FGF/FGFR alterations in gastrointestinal neoplasms; PTCH mutations and gastrointestinal neoplasms; RUNX3 expression and gastric cancer; role of mucins in gastric carcinogenesis; KIT, PDGFRalpha, and gastrointestinal stromal tumors; intestinal neurofibromatosis; and gastrointestinal tumors in other disorders.
Copyright 2003 Wiley-Liss, Inc.
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